Hidenori Suzuki1, Tsuneo Tamaki2, Masami Nishio3, Shintaro Beppu4, Nobuaki Mukoyama5, Nobuhiro Hanai4, Daisuke Nishikawa4, Yusuke Koide4, Yasuhisa Hasegawa4. 1. Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan hi.suzuki@aichi-cc.jp. 2. Department of East Nagoya Imaging Diagnosis Center, Nagoya, Japan. 3. Department of Radiology, Nagoya Positron Emission Tomography Imaging Center, Nagoya, Japan. 4. Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan. 5. Deparment of Othorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Abstract
BACKGROUND/AIM: To predict survival outcomes of different patients with the same stage of disease is difficult. The possible correlation between 18F-fluorodeoxyglucose (18F-FDG) uptake parameters and survival outcomes was investigated in oral squamous cell carcinoma patients by multivariate analysis adjusted for the pathological stage according to the 8th edition of the tumor-node-metastasis (TNM) classification of the Union for International Cancer Contro. PATIENTS AND METHODS: 18F-FDG-uptake parameters of 28 patients were assessed by positron emission tomography with computed tomography (PET/CT). RESULTS: A peak of standardized uptake value of primary tumor (p-SUVpeak) of ≥14.1 was significantly correlated with shorter overall survival by univariate and multivariate analyses adjusted for the pathological TNM stage. A p-SUVpeak of ≥14.1 was significantly associated with shorter local recurrence-free survival and disease-free survival. CONCLUSION: A higher p-SUVpeak on pretreatment 18F-FDG-PET/CT is a prognostic parameter of identifying lower survival outcomes. Copyright
BACKGROUND/AIM: To predict survival outcomes of different patients with the same stage of disease is difficult. The possible correlation between 18F-fluorodeoxyglucose (18F-FDG) uptake parameters and survival outcomes was investigated in oral squamous cell carcinomapatients by multivariate analysis adjusted for the pathological stage according to the 8th edition of the tumor-node-metastasis (TNM) classification of the Union for International Cancer Contro. PATIENTS AND METHODS: 18F-FDG-uptake parameters of 28 patients were assessed by positron emission tomography with computed tomography (PET/CT). RESULTS: A peak of standardized uptake value of primary tumor (p-SUVpeak) of ≥14.1 was significantly correlated with shorter overall survival by univariate and multivariate analyses adjusted for the pathological TNM stage. A p-SUVpeak of ≥14.1 was significantly associated with shorter local recurrence-free survival and disease-free survival. CONCLUSION: A higher p-SUVpeak on pretreatment 18F-FDG-PET/CT is a prognostic parameter of identifying lower survival outcomes. Copyright
Authors: S E C de Mattos; L F Diel; L S Bittencourt; C E Schnorr; F A Gonçalves; L Bernardi; M L Lamers Journal: Braz J Med Biol Res Date: 2021-01-25 Impact factor: 2.590
Authors: Roland M Martens; Thomas Koopman; Cristina Lavini; Tim van de Brug; Gerben J C Zwezerijnen; J Tim Marcus; Marije R Vergeer; C René Leemans; Remco de Bree; Pim de Graaf; Ronald Boellaard; Jonas A Castelijns Journal: Cancers (Basel) Date: 2022-01-03 Impact factor: 6.639