Literature DB >> 30150002

Genetic Crosses and Linkage Mapping in Schistosome Parasites.

Timothy J C Anderson1, Philip T LoVerde2, Winka Le Clec'h3, Frédéric D Chevalier3.   

Abstract

Linkage mapping - utilizing experimental genetic crosses to examine cosegregation of phenotypic traits with genetic markers - is now 100 years old. Schistosome parasites are exquisitely well suited to linkage mapping approaches because genetic crosses can be conducted in the laboratory, thousands of progeny are produced, and elegant experimental work over the last 75 years has revealed heritable genetic variation in multiple biomedically important traits such as drug resistance, host specificity, and virulence. Application of this approach is timely because the improved genome assembly for Schistosoma mansoni and developing molecular toolkit for schistosomes increase our ability to link phenotype with genotype. We describe current progress and potential future directions of linkage mapping in schistosomes.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Schistosoma; fine mapping; functional analysis; heritability; linkage; phenotype

Mesh：

Substances：

Year:  2018        PMID： 30150002      PMCID： PMC6382074          DOI： 10.1016/j.pt.2018.08.001

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN： 1471-4922


  10 in total

1.  Genetic analysis of praziquantel response in schistosome parasites implicates a transient receptor potential channel.

Authors:  Winka Le Clec'h; Frédéric D Chevalier; Ana Carolina A Mattos; Amanda Strickland; Robbie Diaz; Marina McDew-White; Claudia M Rohr; Safari Kinung'hi; Fiona Allan; Bonnie L Webster; Joanne P Webster; Aidan M Emery; David Rollinson; Amadou Garba Djirmay; Khalid M Al Mashikhi; Salem Al Yafae; Mohamed A Idris; Hélène Moné; Gabriel Mouahid; Philip LoVerde; Jonathan S Marchant; Timothy J C Anderson
Journal:  Sci Transl Med       Date:  2021-12-22       Impact factor: 19.319

Review 2.  High-content approaches to anthelmintic drug screening.

Authors:  Mostafa Zamanian; John D Chan
Journal:  Trends Parasitol       Date:  2021-06-03

3.  Striking differences in virulence, transmission and sporocyst growth dynamics between two schistosome populations.

Authors:  Winka Le Clecʼh; Robbie Diaz; Frédéric D Chevalier; Marina McDew-White; Timothy J C Anderson
Journal:  Parasit Vectors       Date:  2019-10-16       Impact factor: 3.876

4.  Extreme-QTL mapping of monepantel resistance in Haemonchus contortus.

Authors:  Simone Cristina Méo Niciura; Polyana Cristine Tizioto; Caroline Valério Moraes; Giovanna Gabrielle Cruvinel; Ana Cláudia Alexandre de Albuquerque; Raul Costa Mascarenhas Santana; Ana Carolina de Souza Chagas; Sergio Novita Esteves; Magda Vieira Benavides; Alessandro Francisco Talamini do Amarante
Journal:  Parasit Vectors       Date:  2019-08-14       Impact factor: 3.876

5.  Population genetic structure of Schistosoma haematobium and Schistosoma haematobium × Schistosoma bovis hybrids among school-aged children in Côte d'Ivoire.

Authors:  Etienne K Angora; Alexane Vangraefschepe; Jean-François Allienne; Hervé Menan; Jean T Coulibaly; Aboulaye Meïté; Giovanna Raso; Mirko S Winkler; William Yavo; André O Touré; Eliézer K N'Goran; Jakob Zinsstag; Jürg Utzinger; Oliver Balmer; Jérôme Boissier
Journal:  Parasite       Date:  2022-05-03       Impact factor: 3.020

6.  Genomic analysis of a parasite invasion: Colonization of the Americas by the blood fluke Schistosoma mansoni.

Authors:  Roy N Platt; Winka Le Clec'h; Frédéric D Chevalier; Marina McDew-White; Philip T LoVerde; Rafael Ramiro de Assis; Guilherme Oliveira; Safari Kinung'hi; Amadou Garba Djirmay; Michelle L Steinauer; Anouk Gouvras; Muriel Rabone; Fiona Allan; Bonnie L Webster; Joanne P Webster; Aidan M Emery; David Rollinson; Timothy J C Anderson
Journal:  Mol Ecol       Date:  2022-02-25       Impact factor: 6.622

7.  Schistosoma mansoni.

Authors:  Timothy J C Anderson; Egie E Enabulele
Journal:  Trends Parasitol       Date:  2020-07-23

8.  Genetic architecture of transmission stage production and virulence in schistosome parasites.

Authors:  Winka Le Clec'h; Frédéric D Chevalier; Marina McDew-White; Vinay Menon; Grace-Ann Arya; Timothy J C Anderson
Journal:  Virulence       Date:  2021-12       Impact factor: 5.882

Review 9.  Extracellular Vesicles Could Carry an Evolutionary Footprint in Interkingdom Communication.

Authors:  Ricardo Correa; Zuleima Caballero; Luis F De León; Carmenza Spadafora
Journal:  Front Cell Infect Microbiol       Date:  2020-03-03       Impact factor: 5.293

Review 10.  Genomics of the Parasitic Nematode Ascaris and Its Relatives.

Authors:  Jianbin Wang
Journal:  Genes (Basel)       Date:  2021-03-28       Impact factor: 4.096
  10 in total

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