Literature DB >> 30149968

Toxicology of Frequently Encountered Nonsteroidal Anti-inflammatory Drugs in Dogs and Cats: An Update.

Mary Kay McLean1, Safdar A Khan2.   

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are used for their antipyretic, anti-inflammatory, and analgesic properties. Although most NSAIDs consist of a range of pharmacologically active agents with diverse chemical structures and properties, they have similar therapeutic and adverse effects associated with their use. Each year, the American Society for the Prevention of Cruelty to Animals Animal Poison Control Center (APCC) receives hundreds of cases involving acute accidental ingestion/overdose of NSAIDs in dogs and cats. This article provides an overview on the classification, uses, pharmacokinetics, mechanisms of action, and treatment of the most commonly encountered NSAIDs in dogs and cats.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Cats; Dogs; Incidents; Nonsteroidal anti-inflammatory drugs; Toxicology; Treatment

Mesh：

Substances：

Year:  2018        PMID： 30149968     DOI： 10.1016/j.cvsm.2018.06.003

Source DB:  PubMed          Journal:  Vet Clin North Am Small Anim Pract        ISSN： 0195-5616            Impact factor:   2.093


  8 in total

1.  Long-term safety evaluation of Daxocox® tablets (enflicoxib) in dogs after weekly oral administrations for seven months.

Authors:  Josep Homedes; Marta Salichs; Antonio Guzman
Journal:  BMC Vet Res       Date:  2021-06-03       Impact factor: 2.741

2.  Association of clinical characteristics and lifestyle factors with fecal S100/calgranulin concentrations in healthy dogs.

Authors:  Romy M Heilmann; Melissa M Guard; Linda Toresson; Stefan Unterer; Aurélien Grellet; Niels Grützner; Jan S Suchodolski; Joerg M Steiner
Journal:  Vet Med Sci       Date:  2021-03-10

3.  A prospective randomized study of efficacy of 2 treatment protocols in preventing recurrence of clinical signs in 51 male cats with obstructive idiopathic cystitis.

Authors:  Ran Nivy; Gilad Segev; Dar Rimer; Yaron Bruchim; Itamar Aroch; Michal Mazaki-Tovi
Journal:  J Vet Intern Med       Date:  2019-08-10       Impact factor: 3.333

Review 4.  Drug-Dosing Adjustment in Dogs and Cats with Chronic Kidney Disease.

Authors:  Francesca De Santis; Andrea Boari; Francesco Dondi; Paolo Emidio Crisi
Journal:  Animals (Basel)       Date:  2022-01-21       Impact factor: 2.752

5.  Selective inhibition of cyclooxygenase-2 by enflicoxib, its enantiomers and its main metabolites in vitro in canine blood.

Authors:  Josep Solà; Àngel Menargues; Josep Homedes; Marta Salichs; Inés Álvarez; Luz Romero; José Miguel Vela
Journal:  J Vet Pharmacol Ther       Date:  2022-01-17       Impact factor: 1.567

6.  Outcomes of nonsteroidal anti-inflammatory drug toxicosis treated with therapeutic plasma exchange in 62 dogs.

Authors:  Emmanuelle M Butty; Steven E Suter; Nolan V Chalifoux; Alex M Lynch; Katie D Mauro; Rachel B Moyle; Caryn M Ehrhardt; James B Robertson; Christine A Culler; Leonel A Londoño; Alessio Vigani; Yu Ueda; Mary A Labato
Journal:  J Vet Intern Med       Date:  2022-08-05       Impact factor: 3.175

7.  Selection of Potent Inhibitors of Soluble Epoxide Hydrolase for Usage in Veterinary Medicine.

Authors:  Diyala S Shihadih; Todd R Harris; Sean D Kodani; Sung-Hee Hwang; Kin Sing Stephen Lee; Vengai Mavangira; Briana Hamamoto; Alonso Guedes; Bruce D Hammock; Christophe Morisseau
Journal:  Front Vet Sci       Date:  2020-08-26

8.  Frunevetmab, a felinized anti-nerve growth factor monoclonal antibody, for the treatment of pain from osteoarthritis in cats.

Authors:  Margaret E Gruen; Jamie A E Myers; Jezaniah-Kira S Tena; Csilla Becskei; Dawn M Cleaver; B Duncan X Lascelles
Journal:  J Vet Intern Med       Date:  2021-11-01       Impact factor: 3.333
  8 in total

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