Literature DB >> 30148096

The Impact of Thyroiditis on Morbidity and Safety in Patients Undergoing Total Thyroidectomy.

Krishnan Ravikumar1, Sankaran Muthukumar2, Dhalapathy Sadacharan3, Umadevi Suresh3, Thalavai Sundarram3, Selladurai Periyasamy3.   

Abstract

BACKGROUND: The indications for surgery in thyroiditis vary from compressive symptoms to cosmesis. We analyzed the complications in patients who underwent total thyroidectomy (TT) in goiters associated with thyroiditis.
MATERIALS AND METHODS: This retrospective study was done in an endocrine surgical center over 4 years. A total of 724 patients, who underwent TT for benign thyroid disorders, were included in the study. Patients were divided into two groups based on histopathology into Group A (nonthyroiditis cases) and Group B (thyroiditis cases); Group B is subdivided into Group B1 (nodular goiter with associated thyroiditis) and Group B2 (Hashimoto's thyroiditis). The preoperative parameters analyzed were serum calcium, serum Vitamin D, serum parathyroid hormone (PTH), and vocal cord status. The intraoperative parameters observed were operating time, parathyroid preservation, and autotransplantation and course of recurrent laryngeal nerve (RLN). Postoperative parameters monitored were serum calcium, serum PTH, serum magnesium, signs and symptoms of hypocalcemia, and vocal cord status. Follow-up was done at 6 months with serum calcium, serum PTH, and video laryngoscopy.
RESULTS: Both groups were age and sex matched. All preoperative and intraoperative parameters were comparable among groups. Both transient complications (<6 months) were higher in Group B than A. Transient hypocalcemia was higher in Group B (39.70%) than Group A (24.77%) (P = 0.001). Transient hypocalcemia was higher in Group B1 (36.58%) than Group B2 (44.44%) (P = 0.014). Transient RLN palsy was higher in Group B (9.55%) than Group A (7.52%) (P = 0.040). Transient RLN palsy was higher in Group B1 (8.53%) than Group B2 (11.11%) (P = 0.039). Permanent hypoparathyroidism and permanent RLN palsy were comparable between the Groups A and B and between Groups B1 and B2.
CONCLUSION: The incidences of transient complications are higher in patients with thyroiditis. Careful analysis of surgical indications will avoid unnecessary surgery in thyroiditis cases.

Entities:  

Keywords:  Hypocalcemia; recurrent laryngeal nerve palsy; thyroiditis

Year:  2018        PMID: 30148096      PMCID: PMC6085970          DOI: 10.4103/ijem.IJEM_209_17

Source DB:  PubMed          Journal:  Indian J Endocrinol Metab        ISSN: 2230-9500


  12 in total

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6.  Experimental study on the effects of chronic iodine excess on thyroid function, structure, and autoimmunity in autoimmune-prone NOD.H-2h4 mice.

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8.  Is thyroidectomy in patients with Hashimoto thyroiditis more risky?

Authors:  Catherine McManus; Jie Luo; Rebecca Sippel; Herbert Chen
Journal:  J Surg Res       Date:  2012-10-01       Impact factor: 2.192

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Authors:  Hiroshi E Takami; Rika Miyabe; Kaori Kameyama
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  1 in total

1.  The significance of Hashimoto's thyroiditis for postoperative complications of thyroid surgery: a systematic review and meta-analysis.

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  1 in total

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