Literature DB >> 30147982

Kidney Transplantation after Extended Multivisceral Resection for Pancreatic Ductal Adenocarcinoma.

Hryhoriy Lapshyn1, Louisa Bolm1, Martin Nitschke2, Andreas M Luebke3, Jakob R Izbicki4, Yogesh K Vashist4,5, Tobias Keck1, Ulrich F Wellner1.   

Abstract

Long-term survival in patients with pancreatic ductal adenocarcinoma (PDAC) is limited. Consequently, solid organ transplantation in PDAC patients is usually not considered. This is the first case report of kidney transplantation (KT) in a 57-year-old female patient after extended multivisceral resection for PDAC of the distal pancreas who had developed end-stage renal disease (ESRD) due to toxic kidney damage by chemotherapy. 13,5 years after initial PDAC-operation and 3 years after KT the patient remains in a good general health condition with sufficient function of the kidney allograft without local tumor recurrence or distant metastasis.

Entities:  

Year:  2018        PMID: 30147982      PMCID: PMC6083642          DOI: 10.1155/2018/3757382

Source DB:  PubMed          Journal:  Case Rep Transplant        ISSN: 2090-6951


  6 in total

1.  Pancreatic cancer in 2017: Rebooting pancreatic cancer knowledge and treatment options.

Authors:  Alexander Semaan; Anirban Maitra
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2018-01-10       Impact factor: 46.802

Review 2.  Pancreatic adenocarcinoma.

Authors:  David P Ryan; Theodore S Hong; Nabeel Bardeesy
Journal:  N Engl J Med       Date:  2014-09-11       Impact factor: 91.245

Review 3.  Pro- and anti-cancer effects of immunosuppressive agents used in organ transplantation.

Authors:  Markus Guba; Christian Graeb; Karl-Walter Jauch; Edward K Geissler
Journal:  Transplantation       Date:  2004-06-27       Impact factor: 4.939

4.  Pancreatic cancer: why is it so hard to treat?

Authors:  Paul E Oberstein; Kenneth P Olive
Journal:  Therap Adv Gastroenterol       Date:  2013-07       Impact factor: 4.409

Review 5.  Treatment of Locally Advanced Pancreatic Ductal Adenocarcinoma.

Authors:  Andrew P Loehrer; Cristina R Ferrone
Journal:  Dig Surg       Date:  2016-05-25       Impact factor: 2.588

Review 6.  Kidney transplantation in patients with history of malignancy: Time to rethink the guidelines?

Authors:  Emily Baiyee; John Mark Sloan
Journal:  Front Biosci (Elite Ed)       Date:  2015-06-01
  6 in total

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