Yvonne A W Hartman1, Esther G A Karssemeijer2,3, Lisanne A M van Diepen1, Marcel G M Olde Rikkert2,3, Dick H J Thijssen1,4. 1. Department of Physiology, Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands. 2. Department of Geriatric Medicine, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Center, Nijmegen, the Netherlands. 3. Radboudumc Alzheimer Center, Radboud University Medical Center, Nijmegen, the Netherlands. 4. Research Institute for Sport and Exercise Sciences, Liverpool John Moores University, Liverpool, United Kingdom.
Abstract
AIMS: The aim of this study was to examine physical activity and sedentary behaviour characteristics of ambulatory and community-dwelling patients with dementia compared to cognitively healthy age-, sex- and weight-matched controls. METHODS: In this cross-sectional study, we included community-dwelling dementia patients (n = 45, age 79.6 ± 5.9 years, Mini-Mental State Examination [MMSE] 22.8 ± 3.2) and matched controls (n = 49, age 80.0 ± 7.7 years, MMSE 29.0 ± 1.2). Participants wore a wrist accelerometer for 7 days to assess sedentary time, sedentary bout duration and time spent in very light, light-to-moderate and moderate-to-vigorous physical activities. RESULTS: Relative sedentary time and sedentary bout duration was significantly higher in dementia patients than in controls (median [interquartile range] 57% [49-68] vs. 55% [47-59] and 18.3 [16.4-21.1] min vs. 16.6 [15.3-18.4] min, p = 0.042 and p = 0.008, respectively). In addition, dementia patients spent a lower percentage of their waking time in light-to-moderate and moderate-to-vigorous intensity physical activities (20% [15-23] vs. 22% [18-25] and 5% [2-10] vs. 10% [5-13], p = 0.017 and p = 0.001, respectively). CONCLUSION: We revealed that dementia patients are more sedentary and perform less physical activity than cognitively healthy controls. This may have clinically important consequences, given the observation that sedentary behaviour and little physical activity independently predict all-cause mortality and morbidity.
AIMS: The aim of this study was to examine physical activity and sedentary behaviour characteristics of ambulatory and community-dwelling patients with dementia compared to cognitively healthy age-, sex- and weight-matched controls. METHODS: In this cross-sectional study, we included community-dwelling dementiapatients (n = 45, age 79.6 ± 5.9 years, Mini-Mental State Examination [MMSE] 22.8 ± 3.2) and matched controls (n = 49, age 80.0 ± 7.7 years, MMSE 29.0 ± 1.2). Participants wore a wrist accelerometer for 7 days to assess sedentary time, sedentary bout duration and time spent in very light, light-to-moderate and moderate-to-vigorous physical activities. RESULTS: Relative sedentary time and sedentary bout duration was significantly higher in dementiapatients than in controls (median [interquartile range] 57% [49-68] vs. 55% [47-59] and 18.3 [16.4-21.1] min vs. 16.6 [15.3-18.4] min, p = 0.042 and p = 0.008, respectively). In addition, dementiapatients spent a lower percentage of their waking time in light-to-moderate and moderate-to-vigorous intensity physical activities (20% [15-23] vs. 22% [18-25] and 5% [2-10] vs. 10% [5-13], p = 0.017 and p = 0.001, respectively). CONCLUSION: We revealed that dementiapatients are more sedentary and perform less physical activity than cognitively healthy controls. This may have clinically important consequences, given the observation that sedentary behaviour and little physical activity independently predict all-cause mortality and morbidity.
Authors: Patricia Manns; Victor Ezeugwu; Susan Armijo-Olivo; Jeff Vallance; Genevieve N Healy Journal: J Am Geriatr Soc Date: 2015-07-14 Impact factor: 5.562
Authors: Sid E O'Bryant; Joy D Humphreys; Glenn E Smith; Robert J Ivnik; Neill R Graff-Radford; Ronald C Petersen; John A Lucas Journal: Arch Neurol Date: 2008-07
Authors: Helena J M van Alphen; Karin M Volkers; Christiaan G Blankevoort; Erik J A Scherder; Tibor Hortobágyi; Marieke J G van Heuvelen Journal: PLoS One Date: 2016-03-31 Impact factor: 3.240
Authors: Carlijn M Maasakkers; Jurgen A H R Claassen; Siobhan Scarlett; Dick H J Thijssen; Rose Anne Kenny; Joanne Feeney; René J F Melis Journal: Prev Med Rep Date: 2021-07-01