Literature DB >> 30144522

The Gut Microbiome in Pancreatic Disease.

Venkata S Akshintala1, Rupjyoti Talukdar2, Vikesh K Singh1, Michael Goggins3.   

Abstract

The gut microbiome increasingly is recognized for its role in human health and disease. Initial evidence has indicated that gut microbial dysbiosis is associated with several pancreatic diseases. Although it is not known if these associations are causative, gut dysbiosis is hypothesized to mediate chronic proinflammatory changes in the pancreas. Further mechanistic and epidemiologic studies of the microbiome are needed. Ultimately, targeted modulation of the microbiota could have therapeutic value.
Copyright © 2019 AGA Institute. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Dysbiosis; Intratumoral Bacteria; Microbiome; Pancreatic Cancer; Pancreatitis; Probiotics

Year:  2018        PMID： 30144522      PMCID： PMC6314887          DOI： 10.1016/j.cgh.2018.08.045

Source DB:  PubMed          Journal:  Clin Gastroenterol Hepatol        ISSN： 1542-3565            Impact factor:   11.382


  72 in total

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