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Literature DB >> 3013757

DNA-diagnosis of sickle cell anemia from chorionic villi: possible influence of maternal cell contamination.

Abstract

The admixture of maternal tissue is a possible hazard of prenatal diagnosis from chorionic villi. Therefore the tolerable degree of maternal DNA contamination in prenatal diagnosis of sickle cell anemia was investigated by mixing various amounts of DNA from HbS carriers with DNA from normal individuals and sickle cell anemia patients. The results indicate that lower rate of admixed maternal DNA does not prevent an exact direct DNA-diagnosis of sickle cell anemia.

Entities: Disease Species

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Year: 1986 PMID： 3013757 DOI： 10.1007/bf00291613

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

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References

17 in total

1. First-trimester diagnosis on chorionic villi obtained by direct vision technique.

Authors: B Gustavii; M A Chester; H Edvall; S Iosif; U Kristoffersson; L Löfberg; A Mineur; F Mitelman
Journal: Hum Genet Date: 1984 Impact factor: 4.132

2. A sensitive new prenatal test for sickle-cell anemia.

Authors: J C Chang; Y W Kan
Journal: N Engl J Med Date: 1982-07-01 Impact factor: 91.245

Review 3. Recent developments in the prenatal diagnosis of genetic diseases and birth defects.

Authors: C J Epstein; D R Cox; S A Schonberg; W A Hogge
Journal: Annu Rev Genet Date: 1983 Impact factor: 16.830

4. Linkage of beta-thalassaemia mutations and beta-globin gene polymorphisms with DNA polymorphisms in human beta-globin gene cluster.

Authors: S H Orkin; H H Kazazian; S E Antonarakis; S C Goff; C D Boehm; J P Sexton; P G Waber; P J Giardina
Journal: Nature Date: 1982-04-15 Impact factor: 49.962

5. Analysis of the Hb M Milwaukee mutation at the DNA level.

Authors: J Horst; R Schäfer; E Kleihauer; E Kohne
Journal: Br J Haematol Date: 1983-08 Impact factor: 6.998

6. Efficient direct chromosome analyses and enzyme determinations from chorionic villi samples in the first trimester of pregnancy.

Authors: G Simoni; B Brambati; C Danesino; F Rossella; G L Terzoli; M Ferrari; M Fraccaro
Journal: Hum Genet Date: 1983 Impact factor: 4.132

DNA-diagnosis of sickle cell anemia from chorionic villi: possible influence of maternal cell contamination.

1. First-trimester diagnosis on chorionic villi obtained by direct vision technique.

2. A sensitive new prenatal test for sickle-cell anemia.

Review 3. Recent developments in the prenatal diagnosis of genetic diseases and birth defects.

4. Linkage of beta-thalassaemia mutations and beta-globin gene polymorphisms with DNA polymorphisms in human beta-globin gene cluster.

5. Analysis of the Hb M Milwaukee mutation at the DNA level.

6. Efficient direct chromosome analyses and enzyme determinations from chorionic villi samples in the first trimester of pregnancy.

7. Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation.

8. Antenatal diagnosis of sickle cell anaemia by direct analysis of the sickle mutation.

9. beta-Thalassemia due to a deletion of the nucleotide which is substituted in the beta S-globin gene.

10. Method of sampling chorionic villi in first trimester of pregnancy under guidance of real time ultrasound.