Literature DB >> 30136229

Methods for Studying TNF-Mediated Necroptosis in Cultured Cells.

Zikou Liu1,2, John Silke3,4, Joanne M Hildebrand5,6.   

Abstract

Necroptosis is a caspase-independent form of programmed cell death that is induced by a variety of different signalling cascades-all culminating in the activation of the pseudokinase mixed lineage kinase domain-like (MLKL). TNF-induced necroptosis is the most intensively studied of these pathways. Here we describe reagents and cell-based techniques that can be used to investigate TNF-mediated necroptosis in the lab.

Entities:  

Keywords:  BN-PAGE; Cell fractionation; MLKL; Necroptosis; TNF

Mesh:

Substances:

Year:  2018        PMID: 30136229     DOI: 10.1007/978-1-4939-8754-2_5

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  5 in total

1.  Oligomerization-driven MLKL ubiquitylation antagonizes necroptosis.

Authors:  Zikou Liu; Laura F Dagley; Kristy Shield-Artin; Samuel N Young; Aleksandra Bankovacki; Xiangyi Wang; Michelle Tang; Jason Howitt; Che A Stafford; Ueli Nachbur; Cheree Fitzgibbon; Sarah E Garnish; Andrew I Webb; David Komander; James M Murphy; Joanne M Hildebrand; John Silke
Journal:  EMBO J       Date:  2021-10-26       Impact factor: 11.598

Review 2.  Progress in understanding the role of lncRNA in programmed cell death.

Authors:  Na Jiang; Xiaoyu Zhang; Xuejun Gu; Xiaozhuang Li; Lei Shang
Journal:  Cell Death Discov       Date:  2021-02-08

3.  RIPK1 Is Cleaved by 3C Protease of Rhinovirus A and B Strains and Minor and Major Groups.

Authors:  Sarah N Croft; Erin J Walker; Reena Ghildyal
Journal:  Viruses       Date:  2021-11-30       Impact factor: 5.048

4.  Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins.

Authors:  Cliff J Luke; Stephanie Markovina; Misty Good; Ira E Wight; Brian J Thomas; John M Linneman; Wyatt E Lanik; Olga Koroleva; Maggie R Coffman; Mark T Miedel; Qingqing Gong; Arlise Andress; Marlene Campos Guerrero; Songyan Wang; LiYun Chen; Wandy L Beatty; Kelsey N Hausmann; Frances V White; James A J Fitzpatrick; Anthony Orvedahl; Stephen C Pak; Gary A Silverman
Journal:  Commun Biol       Date:  2022-01-12

5.  Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers.

Authors:  Ling F Ye; Kunal R Chaudhary; Fereshteh Zandkarimi; Andrew D Harken; Connor J Kinslow; Pavan S Upadhyayula; Athanassios Dovas; Dominique M Higgins; Hui Tan; Yan Zhang; Manuela Buonanno; Tony J C Wang; Tom K Hei; Jeffrey N Bruce; Peter D Canoll; Simon K Cheng; Brent R Stockwell
Journal:  ACS Chem Biol       Date:  2020-01-14       Impact factor: 4.634

  5 in total

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