| Literature DB >> 30134197 |
Lucille C Rankin1, Nicholas Arpaia2.
Abstract
Intestinal Treg cells suppress colitis; yet the mechanisms behind the intricate pathways involved in this process remain largely unknown. In this issue of Immunity,Bauché et al. (2018) show that Treg cells engage MHCII on CX3CR1+ macrophages via LAG3. This indirectly reduces IL-22 mediated colonic inflammation.Entities:
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Year: 2018 PMID： 30134197 DOI： 10.1016/j.immuni.2018.08.008
Source DB: PubMed Journal: Immunity ISSN： 1074-7613 Impact factor: 31.745