Literature DB >> 3013396

Peripheral neuropathy associated with high-dose Ara-C therapy.

A Borgeat, B De Muralt, M Stalder.   

Abstract

Central nervous system toxicity associated with high-dose cytosine arabinoside (Ara-C) therapy (HD Ara-C) is well known. The authors report the case of a severe isolated peripheral polyneuropathy due to HD Ara-C. Electrophysiologic changes and histologic observations were consistent with axonal degeneration and scattered destruction of myelin sheaths. This observation emphasizes the need for careful complete neurologic evaluation for patients receiving HD Ara-C treatment.

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Year:  1986        PMID： 3013396     DOI： 10.1002/1097-0142(19860815)58:4<852::aid-cncr2820580408>3.0.co;2-i

Source DB:  PubMed          Journal:  Cancer        ISSN： 0008-543X            Impact factor:   6.860


  8 in total

1.  Polyneuritis after HD Ara-C therapy for malignant lymphoma.

Authors:  L Montalbetti; G Brambilla Pisoni; G Trotti; M V Calloni
Journal:  Ital J Neurol Sci       Date:  1992-02

Review 2.  High-dose cytosine arabinoside: pharmacological and clinical aspects.

Authors:  W G Peters; L P Colly; R Willemze
Journal:  Blut       Date:  1988-01

3.  Phase I and pharmacokinetic study of 3'-C-ethynylcytidine (TAS-106), an inhibitor of RNA polymerase I, II and III,in patients with advanced solid malignancies.

Authors:  Lisa A Hammond-Thelin; Melanie B Thomas; Michiko Iwasaki; James L Abbruzzese; Yvonne Lassere; Christina A Meyers; Paulo Hoff; Johann de Bono; Jody Norris; Hitoshi Matsushita; Akira Mita; Eric K Rowinsky
Journal:  Invest New Drugs       Date:  2010-09-14       Impact factor: 3.850

Review 4.  The double-edged sword: Neurotoxicity of chemotherapy.

Authors:  Rajiv S Magge; Lisa M DeAngelis
Journal:  Blood Rev       Date:  2014-09-28       Impact factor: 8.250

Review 5.  The toxicity of cytarabine.

Authors:  J Stentoft
Journal:  Drug Saf       Date:  1990 Jan-Feb       Impact factor: 5.606

Review 6.  Neurotoxic complications of chemotherapy in patients with cancer: clinical signs and optimal management.

Authors:  Carla C P Verstappen; Jan J Heimans; Klaas Hoekman; Tjeerd J Postma
Journal:  Drugs       Date:  2003       Impact factor: 9.546

Review 7.  Effects of lymphoma on the peripheral nervous system.

Authors:  R A Hughes; T Britton; M Richards
Journal:  J R Soc Med       Date:  1994-09       Impact factor: 18.000

8.  Ascending sensory motor polyradiculoneuropathy with cranial nerve involvement following administration of intrathecal methotrexate and intravenous cytarabine in a patient with acute myelogenous leukemia: a case report*.

Authors:  Richard A Rison
Journal:  Cases J       Date:  2008-10-21
  8 in total

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