Lucyo Flávio Bezerra Diniz1, Carlos Dornels Freire de Souza2, Rodrigo Feliciano do Carmo1,3. 1. Programa de Pós-Graduação em Ciências da Saúde e Biológicas, Universidade Federal do Vale do São Francisco, Petrolina, PE, Brasil. 2. Faculdade de Medicina, Universidade Federal de Alagoas, Arapiraca, AL, Brasil. 3. Colegiado de Ciências Farmacêuticas, Universidade Federal do Vale do São Francisco, Petrolina, PE, Brasil.
Abstract
INTRODUCTION: Visceral leishmaniasis (VL) is a zoonosis caused by parasites of the Leishmania genus. VL is present in countries with tropical climates, being endemic in Brazil,, including the region of the lower-middle São Francisco Valley which includes the urban centers of Petrolina (Pernambuco state) and Juazeiro (Bahia state). METHODS: This retrospective and descriptive epidemiological study analyzed secondary data obtained from the mandatory visceral leishmaniasis notification forms of the Ministry of Health, which were compiled in the Information System for Notifiable Diseases (SINAN) database. We analyzed 181 autochthonous cases reported in the two aforementioned cities between 2010 and 2016. Data collection occurred in June 2017. RESULTS: Of the 181 VL cases in the study area, 40.9% (n=74) occurred in Juazeiro and 59.1% (n=107) occurred in Petrolina. The average numbers of cases per year were 9.5 in Juazeiro and 14 in Petrolina; respectively, the incidence ranges were 2-8.6 cases and 2.8-6.1 cases per 100,000 inhabitants. Fever, weakness, weight loss, and pallor were the most commonly observed clinical manifestations. Coinfection with human immunodeficiency virus (HIV) was observed in 16.8% and 5.4% of cases in Petrolina and Juazeiro, respectively. The lethality rates were 2.8% and 5.4% in Petrolina and Juazeiro, respectively. CONCLUSIONS: Both cities had a high incidence of VL during the studied period. The findings of this study contribute to a better understanding of the behavior of VL during recent years and may help to direct regional disease control measures.
INTRODUCTION:Visceral leishmaniasis (VL) is a zoonosis caused by parasites of the Leishmania genus. VL is present in countries with tropical climates, being endemic in Brazil,, including the region of the lower-middle São Francisco Valley which includes the urban centers of Petrolina (Pernambuco state) and Juazeiro (Bahia state). METHODS: This retrospective and descriptive epidemiological study analyzed secondary data obtained from the mandatory visceral leishmaniasis notification forms of the Ministry of Health, which were compiled in the Information System for Notifiable Diseases (SINAN) database. We analyzed 181 autochthonous cases reported in the two aforementioned cities between 2010 and 2016. Data collection occurred in June 2017. RESULTS: Of the 181 VL cases in the study area, 40.9% (n=74) occurred in Juazeiro and 59.1% (n=107) occurred in Petrolina. The average numbers of cases per year were 9.5 in Juazeiro and 14 in Petrolina; respectively, the incidence ranges were 2-8.6 cases and 2.8-6.1 cases per 100,000 inhabitants. Fever, weakness, weight loss, and pallor were the most commonly observed clinical manifestations. Coinfection with human immunodeficiency virus (HIV) was observed in 16.8% and 5.4% of cases in Petrolina and Juazeiro, respectively. The lethality rates were 2.8% and 5.4% in Petrolina and Juazeiro, respectively. CONCLUSIONS: Both cities had a high incidence of VL during the studied period. The findings of this study contribute to a better understanding of the behavior of VL during recent years and may help to direct regional disease control measures.
Authors: Samuel R Aquino; Lucyo F B Diniz; Igor T Queiroz; Mirella A Cunha; Alda M Justo; Elis D Silva; Valéria R A Pereira; Zulma M Medeiros; Rodrigo F Carmo Journal: Am J Trop Med Hyg Date: 2020-09-03 Impact factor: 3.707
Authors: Bruno Eduardo Bastos Rolim Nunes; Thiago Cavalcanti Leal; João Paulo Silva de Paiva; Leonardo Feitosa da Silva; Rodrigo Feliciano do Carmo; Michael Ferreira Machado; Maria Deysiane Porto de Araújo; Victor Santana Santos; Carlos Dornels Freire de Souza Journal: Rev Soc Bras Med Trop Date: 2019-12-20 Impact factor: 1.581
Authors: Diego Lins Guedes; Alda Maria Justo; Walter Lins Barbosa Júnior; Elis Dionísio da Silva; Samuel Ricarte de Aquino; Manoel Sebastiao da Costa Lima Junior; Ulisses Montarroyos; Gilberto Silva Nunes Bezerra; Amanda Virginia Batista Vieira; Valéria Rêgo Alves Pereira; Zulma Maria de Medeiros Journal: PLoS Negl Trop Dis Date: 2021-01-21