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Literature DB >> 3013088

Comparison of susceptibilities of varicella-zoster virus and herpes simplex viruses to nucleoside analogs.

Abstract

The susceptibilities of varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) to 17 nucleoside analogs were compared by a plaque reduction assay with human embryonic lung fibroblast cells. The susceptibility of VZV to certain nucleoside analogs was different from that of HSV-1. Against VZV the 5-halogenovinyl-arabinosyluracils were the most potent of the compounds tested.

Entities: Chemical Disease Species

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Year: 1986 PMID： 3013088 PMCID： PMC180428 DOI： 10.1128/AAC.29.3.524

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

12 in total

1. Comparative efficacy of antiherpes drugs against different strains of herpes simplex virus.

Authors: E De Clercq; J Descamps; G Verhelst; R T Walker; A S Jones; P F Torrence; D Shugar
Journal: J Infect Dis Date: 1980-05 Impact factor: 5.226

2. Induction of thymidine kinase and DNase in varicella-zoster virus-infected cells and kinetic properties of the virus-induced thymidine kinase.

Authors: Y C Cheng; T Y Tsou; T Hackstadt; L P Mallavia
Journal: J Virol Date: 1979-07 Impact factor: 5.103

3. In vitro and in vivo antiviral activity of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (BV-araU) and related compounds.

Authors: H Machida; S Sakata
Journal: Antiviral Res Date: 1984-06 Impact factor: 5.970

4. Induction of deoxypyrimidine kinase activity in human embryonic lung cells infected with varicella-zoster virus.

Authors: T Ogino; T Otsuka; M Takahashi
Journal: J Virol Date: 1977-03 Impact factor: 5.103

5. Comparative efficacy of antiherpes drugs in different cell lines.

Authors: E De Clercq
Journal: Antimicrob Agents Chemother Date: 1982-04 Impact factor: 5.191

6. In vitro susceptibility of varicella-zoster virus to E-5-(2-bromovinyl)-2'-deoxyuridine and related compounds.

Authors: E De Clercq; J Descamps; M Ogata; S Shigeta
Journal: Antimicrob Agents Chemother Date: 1982-01 Impact factor: 5.191

7. Inhibitory effects of antiherpesviral thymidine analogs against varicella-zoster virus.

Authors: H Machida; A Kuninaka; H Yoshino
Journal: Antimicrob Agents Chemother Date: 1982-02 Impact factor: 5.191

8. Comparative efficacy of antiherpes drugs against various strains of varicella-zoster virus.

Authors: S Shigeta; T Yokota; T Iwabuchi; M Baba; K Konno; M Ogata; E De Clercq
Journal: J Infect Dis Date: 1983-03 Impact factor: 5.226

9. Synthesis and antiherpesviral activity of 5-C-substituted uracil nucleosides.

Authors: S Sakata; S Shibuya; H Machida; H Yoshino; K Hirota; S Senda; K Ikeda; Y Mizuno
Journal: Nucleic Acids Symp Ser Date: 1980

10. Antiherpesviral and anticellular effects of 1-beta-D-arabinofuranosyl-E-5-(2-halogenovinyl) uracils.

Authors: H Machida; S Sakata; A Kuninaka; H Yoshino
Journal: Antimicrob Agents Chemother Date: 1981-07 Impact factor: 5.191

16 in total

1. The viral thymidine kinase gene as a tool for the study of mutagenesis in Trypanosoma brucei.

Authors: J Valdés; M C Taylor; M A Cross; M J Ligtenberg; G Rudenko; P Borst
Journal: Nucleic Acids Res Date: 1996-05-15 Impact factor: 16.971

2. Rapid phenotypic characterization method for herpes simplex virus and Varicella-Zoster virus thymidine kinases to screen for acyclovir-resistant viral infection.

Authors: T Suzutani; M Saijo; M Nagamine; M Ogasawara; M Azuma
Journal: J Clin Microbiol Date: 2000-05 Impact factor: 5.948

3. Comparison of two bromovinyl nucleoside analogs, 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil and E-5-(2-bromovinyl)-2'-deoxyuridine, with acyclovir in inhibition of Epstein-Barr virus replication.

Authors: J C Lin; H Machida
Journal: Antimicrob Agents Chemother Date: 1988-07 Impact factor: 5.191

4. Effects of various nucleosides on antiviral activity and metabolism of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil against herpes simplex virus types 1 and 2.

Authors: T Suzutani; H Machida; T Sakuma; M Azuma
Journal: Antimicrob Agents Chemother Date: 1988-10 Impact factor: 5.191

5. Efficacies of antiherpesvirus nucleosides against two strains of herpes simplex virus type 1 in Vero and human embryo lung fibroblast cells.

Authors: T Suzutani; H Machida; T Sakuma
Journal: Antimicrob Agents Chemother Date: 1988-07 Impact factor: 5.191

6. Effect of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil (brovavir) on experimental infections in mice with herpes simplex virus type 1 strains of different degrees of virulence.

Authors: H Machida; J Takezawa
Journal: Antimicrob Agents Chemother Date: 1990-05 Impact factor: 5.191