Nikos K Karamanos1, Achilleas D Theocharis2, Thomas Neill3, Renato V Iozzo3. 1. Biochemistry, Biochemical Analysis and Matrix Pathobiochemistry Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26500 Patras, Greece. Electronic address: n.k.karamanos@upatras.gr. 2. Biochemistry, Biochemical Analysis and Matrix Pathobiochemistry Research Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26500 Patras, Greece. 3. Department of Pathology, Anatomy, and Cell Biology, Cancer Cell Biology and Signaling Program, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA 19107, USA.
Abstract
The overall structure and architecture of the extracellular matrix undergo dramatic alterations in composition, form, and functionality over time. The stochasticity begins during development, essential for maintaining organismal homeostasis and is heavily implicated in many pathobiological states including fibrosis and cancer. Modeling and remodeling of the matrix is driven by the local cellular milieu and secreted and cell-associated components in a framework of dynamic reciprocity. This collection of expertly-written reviews aims to relay state-of-the-art information concerning the mechanisms of matrix modeling and remodeling in physiological development and disease.
The overall structure and architecture of the extracellular matrix undergo dramatic alterations in composition, form, and functionality over time. The stochasticity begins during development, essential for maintaining organismal homeostasis and is heavily implicated in many pathobiological states including fibrosis and n class="Disease">cancer. Modeling and remodeling of the matrix is driven by the local cellular milieu and secreted and cell-associated components in a framework of dynamic reciprocity. This collection of expertly-written reviews aims to relay state-of-the-art information concerning the mechanisms of matrix modeling and remodeling in physiological development and disease.
Authors: Cédric Zeltz; Stéphane Brézillon; Jarmo Käpylä; Johannes A Eble; Hélène Bobichon; Christine Terryn; Corinne Perreau; Clemens M Franz; Jyrki Heino; François-Xavier Maquart; Yanusz Wegrowski Journal: Exp Cell Res Date: 2010-08-10 Impact factor: 3.905
Authors: Olga M Viquez; Eugenia M Yazlovitskaya; Tianxiang Tu; Glenda Mernaugh; Pablo Secades; Karen K McKee; Elizabeth Georges-Labouesse; Adele De Arcangelis; Vito Quaranta; Peter Yurchenco; Leslie C Gewin; Arnoud Sonnenberg; Ambra Pozzi; Roy Zent Journal: Matrix Biol Date: 2016-12-30 Impact factor: 11.583
Authors: Theodoros T Karalis; Paraskevi Heldin; Demitrios H Vynios; Thomas Neill; Simone Buraschi; Renato V Iozzo; Nikos K Karamanos; Spyros S Skandalis Journal: Matrix Biol Date: 2018-04-16 Impact factor: 11.583
Authors: P C Almeida; I L Nantes; J R Chagas; C C Rizzi; A Faljoni-Alario; E Carmona; L Juliano; H B Nader; I L Tersariol Journal: J Biol Chem Date: 2001-01-12 Impact factor: 5.157
Authors: Kaushlendra Tripathi; Vishnu C Ramani; Shyam K Bandari; Rada Amin; Elizabeth E Brown; Joseph P Ritchie; Mark D Stewart; Ralph D Sanderson Journal: Matrix Biol Date: 2019-12-05 Impact factor: 11.583
Authors: Yayoi Izu; Sheila M Adams; Brianne K Connizzo; David P Beason; Louis J Soslowsky; Manuel Koch; David E Birk Journal: Matrix Biol Date: 2020-10-20 Impact factor: 11.583
Authors: Rui Hua; Qingwen Ni; Travis D Eliason; Yan Han; Sumin Gu; Daniel P Nicolella; Xiaodu Wang; Jean X Jiang Journal: Matrix Biol Date: 2020-09-28 Impact factor: 11.583
Authors: Mahbubul H Shihan; Mallika Kanwar; Yan Wang; Erin E Jackson; Adam P Faranda; Melinda K Duncan Journal: Matrix Biol Date: 2020-03-12 Impact factor: 11.583
Authors: Maria Tsingas; Olivia K Ottone; Abdul Haseeb; Ruteja A Barve; Irving M Shapiro; Véronique Lefebvre; Makarand V Risbud Journal: Matrix Biol Date: 2020-10-04 Impact factor: 11.583