Abhishek Pratap1,2, David C Atkins3, Brenna N Renn3, Michael J Tanana4, Sean D Mooney1, Joaquin A Anguera5, Patricia A Areán3. 1. Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, Washington. 2. Sage Bionetworks, Seattle, Washington. 3. Department of Psychiatry & Behavioral Sciences, University of Washington, Seattle, Washington. 4. Social Research Institute, University of Utah, Salt Lake City, Utah. 5. Department of Neurology, University of California, San Francisco (UCSF), San Francisco, California.
Abstract
BACKGROUND: Smartphones provide a low-cost and efficient means to collect population level data. Several small studies have shown promise in predicting mood variability from smartphone-based sensor and usage data, but have not been generalized to nationally recruited samples. This study used passive smartphone data, demographic characteristics, and baseline depressive symptoms to predict prospective daily mood. METHOD: Daily phone usage data were collected passively from 271 Android phone users participating in a fully remote randomized controlled trial of depression treatment (BRIGHTEN). Participants completed daily Patient Health Questionnaire-2. A machine learning approach was used to predict daily mood for the entire sample and individual participants. RESULTS: Sample-wide estimates showed a marginally significant association between physical mobility and self-reported daily mood (B = -0.04, P < 0.05), but the predictive models performed poorly for the sample as a whole (median R2 ∼ 0). Focusing on individuals, 13.9% of participants showed significant association (FDR < 0.10) between a passive feature and daily mood. Personalized models combining features provided better prediction performance (median area under the curve [AUC] > 0.50) for 80.6% of participants and very strong prediction in a subset (median AUC > 0.80) for 11.8% of participants. CONCLUSIONS: Passive smartphone data with current features may not be suited for predicting daily mood at a population level because of the high degree of intra- and interindividual variation in phone usage patterns and daily mood ratings. Personalized models show encouraging early signs for predicting an individual's mood state changes, with GPS-derived mobility being the top most important feature in the present sample.
RCT Entities:
BACKGROUND: Smartphones provide a low-cost and efficient means to collect population level data. Several small studies have shown promise in predicting mood variability from smartphone-based sensor and usage data, but have not been generalized to nationally recruited samples. This study used passive smartphone data, demographic characteristics, and baseline depressive symptoms to predict prospective daily mood. METHOD: Daily phone usage data were collected passively from 271 Android phone users participating in a fully remote randomized controlled trial of depression treatment (BRIGHTEN). Participants completed daily Patient Health Questionnaire-2. A machine learning approach was used to predict daily mood for the entire sample and individual participants. RESULTS: Sample-wide estimates showed a marginally significant association between physical mobility and self-reported daily mood (B = -0.04, P < 0.05), but the predictive models performed poorly for the sample as a whole (median R2 ∼ 0). Focusing on individuals, 13.9% of participants showed significant association (FDR < 0.10) between a passive feature and daily mood. Personalized models combining features provided better prediction performance (median area under the curve [AUC] > 0.50) for 80.6% of participants and very strong prediction in a subset (median AUC > 0.80) for 11.8% of participants. CONCLUSIONS: Passive smartphone data with current features may not be suited for predicting daily mood at a population level because of the high degree of intra- and interindividual variation in phone usage patterns and daily mood ratings. Personalized models show encouraging early signs for predicting an individual's mood state changes, with GPS-derived mobility being the top most important feature in the present sample.
Keywords:
ambulatory; classification; depression; geographic positioning systems; mobile health (mHealth); monitoring; passive data collection; smartphones
Authors: Rachel Kornfield; Renwen Zhang; Jennifer Nicholas; Stephen M Schueller; Scott A Cambo; David C Mohr; Madhu Reddy Journal: Proc SIGCHI Conf Hum Factor Comput Syst Date: 2020-04
Authors: Craig J Goergen; MacKenzie J Tweardy; Steven R Steinhubl; Stephan W Wegerich; Karnika Singh; Rebecca J Mieloszyk; Jessilyn Dunn Journal: Annu Rev Biomed Eng Date: 2021-12-21 Impact factor: 11.324
Authors: Tijana Sagorac Gruichich; Juan Camilo David Gomez; Gabriel Zayas-Cabán; Melvin G McInnis; Amy L Cochran Journal: Bipolar Disord Date: 2021-02-26 Impact factor: 6.744
Authors: Michael Bauer; Tasha Glenn; John Geddes; Michael Gitlin; Paul Grof; Lars V Kessing; Scott Monteith; Maria Faurholt-Jepsen; Emanuel Severus; Peter C Whybrow Journal: Int J Bipolar Disord Date: 2020-01-10