Literature DB >> 30129304

[New progress in the treatment of chronic wound of diabetic foot].

Jiangning Wang1, Lei Gao2.   

Abstract

Diabetic foot is one of the serious complications of diabetic patients. It is caused by diabetes combined with different degrees of lower extremity vascular lesions and neuropathy, and the wound can not heal for a long time. The serious results can cause bone marrow infection, bone destruction, and have high disability and death rate. At present, there are various treatment methods for diabetic foot chronic wound. On the basis of internal medicine controlling blood sugar, anti infection, lowering blood lipid, improving microcirculation and nourishment nerve, the surgical method is adopted, including the debridement of the necrosis in a short time to prevent the infection from spreading; maggot biological debridement and ozone chemical debridement will promote the growth of granulation tissue while controlling infection. Skin grafting, skin flap transplantation, skin distraction closure can be used to repair soft tissue defects, or fat transplantation, platelet-rich plasma, and rich blood are used for the refractory wound after infection control. In patients with diabetic foot, the reconstruction of lower limb blood supply is beneficial to the recovery of chronic ischemic wounds. It is feasible to improve the blood supply of the lower extremities, improve the blood supply of the lower extremity artery bypass grafting, and improve the microcirculation of the peripheral vessels around the lower extremities. Lower extremity vascular bypass pressure perfusion therapy for vascular network expansion, tibia lateral moving technique for lower limb microcirculation reconstruction. For diabetic foot ulcer caused by peripheral neuropathy, such as Charcot foot, while the application of external fixator, total contact cast technology of affected foot for reducing treatment to promote wound healing; the preparation of orthopedic shoes can play a maximum protective effect on the healing of diabetic foot wound healing.

Entities:  

Keywords:  Diabetic foot; chronic wound; complex treatment

Mesh:

Year:  2018        PMID: 30129304     DOI: 10.7507/1002-1892.201806058

Source DB:  PubMed          Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi        ISSN: 1002-1892


  3 in total

1.  Glucose/ROS cascade-responsive ceria nanozymes for diabetic wound healing.

Authors:  Xiaojuan Yu; Xiaoxue Fu; Jiaxin Yang; Lu Chen; Feng Leng; Zhangyou Yang; Chao Yu
Journal:  Mater Today Bio       Date:  2022-06-02

2.  Comprehensive treatment of diabetic hallux gangrene with lower extremity vascular disease: A case report.

Authors:  Lei Gao; Tianbo Li; Shuo Wang; Jiangning Wang
Journal:  J Int Med Res       Date:  2019-11-26       Impact factor: 1.671

3.  Effects of Moist Exposed Burn Therapy and Ointment (MEBT/MEBO) on the autophagy mTOR signalling pathway in diabetic ulcer wounds.

Authors:  Aitian Zheng; Huadan Ma; Xianbin Liu; Qing Huang; Zheng Li; Lin Wang; Na Zeng; Biaoliang Wu
Journal:  Pharm Biol       Date:  2020-12       Impact factor: 3.503

  3 in total

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