Literature DB >> 30123880

Symptoms Experience and Quality of Life in The Patients With Breast Cancer Receiving The Taxane Class of Drugs.

Kamile Kırca1, Sevinç Kutlutürkan2.   

Abstract

OBJECTIVE: The aim of this study is to evaluate the symptoms experience and quality of life in patients with breast cancer receiving the taxane class of drugs.
MATERIALS AND METHODS: This study was performed between November 2015 March 2016 in a chemotherapy unit of a university hospital with 48 patients, who agreed to participate in the study. The Memorial Symptom Rating Score (MSAS), Socio-demographic and Clinical Features Form, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Breast (EORTC QLQ- BR23) measures specific to breast cancer were used to obtain data.
RESULTS: The average age of the patients was 45.65. The majority of patients were treated with the paclitaxel/paclitaxel+trastuzumab treatment protocol (60.42%), and more than half (54.16%) of these patients were on 5 or 6 treatments. The symptoms patients experienced the most commonly included being sensitive, weakness or energy loss and pain. The symptoms they experienced severely were included fatigue and energy loss and being sensitive. The most distressing symptoms were pain, worry, numbness in hands and feet. The overall well-being score of the patients as per the quality of life findings was 46.18±11.66. While the lowest score for the functional scales was in the social function subscale (66.32±15.18), the highest score for the symptom scales was in the pain subscale (42.01±15.37). The lowest score for the EORTC QLQ-BR23 scales was in the sexual life subscale (20.83±20.19); the highest score was in the body appearance subscale (65.8±23.96).
CONCLUSION: The results of the study are thought to be helpful for the oncology nurses in evaluating the patients in all aspects and in determining priorities for care.

Entities:  

Keywords:  Breast cancer; quality of life; symptom; taxane

Year:  2018        PMID: 30123880      PMCID: PMC6092149          DOI: 10.5152/ejbh.2018.3785

Source DB:  PubMed          Journal:  Eur J Breast Health


  27 in total

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Authors:  A Guzelant; T Goksel; S Ozkok; S Tasbakan; T Aysan; A Bottomley
Journal:  Eur J Cancer Care (Engl)       Date:  2004-05       Impact factor: 2.520

2.  Health-related quality of life in early breast cancer.

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3.  The BCPT symptom scales: a measure of physical symptoms for women diagnosed with or at risk for breast cancer.

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Journal:  J Natl Cancer Inst       Date:  2005-03-16       Impact factor: 13.506

4.  Prevalence and correlates of symptoms and uncertainty in illness among head and neck cancer patients receiving definitive radiation with or without chemotherapy.

Authors:  Mary Ellen Haisfield-Wolfe; Deborah B McGuire; Karen Soeken; Jeanne Geiger-Brown; Bruce De Forge; Mohan Suntharalingam
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5.  TT virus infection and genotype distribution in blood donors and a group of patients from Turkey.

Authors:  S Erensoy; A A Sayiner; S Türkoğlu; D Canatan; U S Akarca; R Sertöz; T Ozacar; Y Batur; S Badur; A Bilgiç
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6.  Chemotherapy-induced peripheral neuropathy as a predictor of neuropathic pain in breast cancer patients previously treated with paclitaxel.

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7.  The Memorial Symptom Assessment Scale: an instrument for the evaluation of symptom prevalence, characteristics and distress.

Authors:  R K Portenoy; H T Thaler; A B Kornblith; J M Lepore; H Friedlander-Klar; E Kiyasu; K Sobel; N Coyle; N Kemeny; L Norton
Journal:  Eur J Cancer       Date:  1994       Impact factor: 9.162

Review 8.  Breast cancer follow-up and management after primary treatment: American Society of Clinical Oncology clinical practice guideline update.

Authors:  James L Khatcheressian; Patricia Hurley; Elissa Bantug; Laura J Esserman; Eva Grunfeld; Francine Halberg; Alexander Hantel; N Lynn Henry; Hyman B Muss; Thomas J Smith; Victor G Vogel; Antonio C Wolff; Mark R Somerfield; Nancy E Davidson
Journal:  J Clin Oncol       Date:  2012-11-05       Impact factor: 44.544

9.  Body image in recently diagnosed young women with early breast cancer.

Authors:  Shoshana M Rosenberg; Rulla M Tamimi; Shari Gelber; Kathryn J Ruddy; Sandra Kereakoglow; Virginia F Borges; Steven E Come; Lidia Schapira; Eric P Winer; Ann H Partridge
Journal:  Psychooncology       Date:  2012-11-07       Impact factor: 3.894

Review 10.  Overview of neuropathy associated with taxanes for the treatment of metastatic breast cancer.

Authors:  Edgardo Rivera; Mary Cianfrocca
Journal:  Cancer Chemother Pharmacol       Date:  2015-01-18       Impact factor: 3.333

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2.  Effects of exercise on chemotherapy-induced peripheral neuropathy in cancer patients: a systematic review and meta-analysis.

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