John E Lonstein1. 1. Department of Orthopedic Surgery, University of Minnesota, Minneapolis MN. Twin Cities Spine Center, Minneapolis, MN; Gillette Specialty Healthcare, St. Paul, MN. Electronic address: lonsteinj@aol.com.
Abstract
STUDY DESIGN: The current literature on outcomes of early fusions for early-onset scoliosis (EOS) has a short follow-up of 7.7 to 12.5 years, with many patients not at the end of growth. The forced vital capacity (FVC) at follow-up ranged from 40.8% to 64% of predicted. A study was undertaken to evaluate the long-term outcome of these fusions. METHODS: The study is of congenital patients who had a fusion under age 8 years, with the current age being >20 years. A follow-up consisting of radiographs, outcome questionnaires, and pulmonary function tests was performed. Of the 42 patients identified, 20 were traced and 11 agreed to participate, and completed all the data. The average follow-up was 37 years. All the fusions included the thoracic spine, with an average of 10.2 levels fused, of which an average of 8.8 levels were thoracic. RESULTS: The average scoliosis at presentation was 52°, 56° at surgery and 47° at follow-up. At follow-up, the average FVC was 53% of predicted, with an average PaO2 of 86 and PaCO2 of 44 mm Hg. The mean T1-T12 length was 20 cm. There was no correlation of the FVC percentage predicted and the proximal extent of the fusion, the T1-T12 length or the number of thoracic levels fused. The average ODI was 23. On the SF36, the average Physical Component t score was 50; with the average Mental Component t score was 52. CONCLUSION: At a long-term average follow-up of 37 years, the patients had a low FVC of 53%, with one on permanent oxygen and 5 with dyspnea. The patients were functioning well at follow-up, but it is unknown what their function would be without surgery or with longer follow-up.
STUDY DESIGN: The current literature on outcomes of early fusions for early-onset scoliosis (EOS) has a short follow-up of 7.7 to 12.5 years, with many patients not at the end of growth. The forced vital capacity (FVC) at follow-up ranged from 40.8% to 64% of predicted. A study was undertaken to evaluate the long-term outcome of these fusions. METHODS: The study is of congenital patients who had a fusion under age 8 years, with the current age being >20 years. A follow-up consisting of radiographs, outcome questionnaires, and pulmonary function tests was performed. Of the 42 patients identified, 20 were traced and 11 agreed to participate, and completed all the data. The average follow-up was 37 years. All the fusions included the thoracic spine, with an average of 10.2 levels fused, of which an average of 8.8 levels were thoracic. RESULTS: The average scoliosis at presentation was 52°, 56° at surgery and 47° at follow-up. At follow-up, the average FVC was 53% of predicted, with an average PaO2 of 86 and PaCO2 of 44 mm Hg. The mean T1-T12 length was 20 cm. There was no correlation of the FVC percentage predicted and the proximal extent of the fusion, the T1-T12 length or the number of thoracic levels fused. The average ODI was 23. On the SF36, the average Physical Component t score was 50; with the average Mental Component t score was 52. CONCLUSION: At a long-term average follow-up of 37 years, the patients had a low FVC of 53%, with one on permanent oxygen and 5 with dyspnea. The patients were functioning well at follow-up, but it is unknown what their function would be without surgery or with longer follow-up.
Authors: Huan Dong; Rajpal Nandra; Dan Thurston; Edward Laugharne; Matthew Newton Ede; Adrian Gardner; Jwalant Mehta Journal: Spine Deform Date: 2021-02-01