Miwako Nomura1, Nobukazu Fuwa2, Yutaka Toyomasu3, Akinori Takada3, Noriko Ii2, Jouji Nomura4, Hiroyuki Yamada5. 1. Department of Radiation Oncology, Ise Red Cross Hospital, 471-2 Funae 1 Choume, Ise-shi, Mie, 516-8512, Japan. mn51ss@gmail.com. 2. Department of Radiation Oncology, Ise Red Cross Hospital, 471-2 Funae 1 Choume, Ise-shi, Mie, 516-8512, Japan. 3. Department of Radiation Oncology, Mie University Hospital, 174 Edobashi 2 Choume, Tsu-shi, Mie, 514-8507, Japan. 4. Department of Oral and Maxillofacial Surgery, Ise Red Cross Hospital, 471-2 Funae 1 Choume, Ise-shi, Mie, 516-8512, Japan. 5. Department of Head and Neck Otorhinolaryngology, Ise Red Cross Hospital, 471-2 Funae 1 Choume, Ise-shi, Mie, 516-8512, Japan.
Abstract
PURPOSE: We developed an external carotid arterial sheath (ECAS) for performing intra-arterial chemotherapy (IACT) via the superficial temporal artery for head and neck cancer. This study aimed to assess the potential of a novel microcatheter with a steerable tip inserted through the ECAS in comparison to an existing hook-type microcatheter. MATERIALS AND METHODS: The same operator used two types of microcatheters alternately for each weekly IACT session with the same patient, and the fluoroscopy time required for catheterization and the arterial selectivity of each microcatheter were compared. RESULTS: Ten patients with advanced head and neck cancer were enrolled. The steerable microcatheter significantly shortened the fluoroscopy time required for catheterization in comparison to the hook-type microcatheter (45.9 ± 4.8 vs 70.2 ± 9.8 s, p < 0.02). The arterial selectivity was equivalent [97.1%, (34/35) vs 88.6%, (31/35), p = 0.36]. No serious adverse events were observed in association with the procedure. CONCLUSION: In combination with an ECAS, the steerable microcatheter might be more useful than the hook-type microcatheter.
PURPOSE: We developed an external carotid arterial sheath (ECAS) for performing intra-arterial chemotherapy (IACT) via the superficial temporal artery for head and neck cancer. This study aimed to assess the potential of a novel microcatheter with a steerable tip inserted through the ECAS in comparison to an existing hook-type microcatheter. MATERIALS AND METHODS: The same operator used two types of microcatheters alternately for each weekly IACT session with the same patient, and the fluoroscopy time required for catheterization and the arterial selectivity of each microcatheter were compared. RESULTS: Ten patients with advanced head and neck cancer were enrolled. The steerable microcatheter significantly shortened the fluoroscopy time required for catheterization in comparison to the hook-type microcatheter (45.9 ± 4.8 vs 70.2 ± 9.8 s, p < 0.02). The arterial selectivity was equivalent [97.1%, (34/35) vs 88.6%, (31/35), p = 0.36]. No serious adverse events were observed in association with the procedure. CONCLUSION: In combination with an ECAS, the steerable microcatheter might be more useful than the hook-type microcatheter.
Entities:
Keywords:
Head and neck cancer; Intra-arterial chemotherapy; The superficial temporal artery
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