Literature DB >> 3012000

The production of focal herpes encephalitis in mice by stereotaxic inoculation of virus. Anatomical and behavioral effects.

D J McFarland, E Sikora, J Hotchin.   

Abstract

A low virulence strain of herpes simplex type 1 was microinjected into the hippocampus of BALB/c mice. Intense replication of virus at the inoculum site was followed by spread of viral antigen to the afferent connections of the hippocampus. Surviving animals showed focal damage of limbic structures and specific behavioral abnormalities generally consistent with hippocampal damage. This procedure thus produces an animal model which more closely resembles human herpes encephalitis than those previously reported.

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Year:  1986        PMID： 3012000     DOI： 10.1016/0022-510x(86)90018-3

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN： 0022-510X            Impact factor:   3.181


  9 in total

1.  Experimental herpes simplex virus encephalitis: a combination therapy of acyclovir and glucocorticoids reduces long-term magnetic resonance imaging abnormalities.

Authors:  Uta K Meyding-Lamadé; Christoph Oberlinner; Philipp R Rau; Sonja Seyfer; Sabine Heiland; Johann Sellner; Brigitte T Wildemann; Wolfram R Lamadé
Journal:  J Neurovirol       Date:  2003-02       Impact factor: 2.643

Review 2.  How neuroscience can inform the study of individual differences in cognitive abilities.

Authors:  Dennis J McFarland
Journal:  Rev Neurosci       Date:  2017-05-24       Impact factor: 4.353

3.  The range and distribution of murine central nervous system cells infected with the gamma(1)34.5- mutant of herpes simplex virus 1.

Authors:  N S Markovitz; D Baunoch; B Roizman
Journal:  J Virol       Date:  1997-07       Impact factor: 5.103

Review 4.  HSV as a gene transfer vector for the nervous system.

Authors:  J C Glorioso; M A Bender; W F Goins; D J Fink; N DeLuca
Journal:  Mol Biotechnol       Date:  1995-08       Impact factor: 2.695

5.  Competitive quantitative PCR analysis of herpes simplex virus type 1 DNA and latency-associated transcript RNA in latently infected cells of the rat brain.

Authors:  R Ramakrishnan; D J Fink; G Jiang; P Desai; J C Glorioso; M Levine
Journal:  J Virol       Date:  1994-03       Impact factor: 5.103

6.  Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation in mice.

Authors:  P Sundaresan; W D Hunter; R L Martuza; S D Rabkin
Journal:  J Virol       Date:  2000-04       Impact factor: 5.103

7.  Pathologic studies and comparison of the virulence of herpes simplex virus type 2 from Okinawa, Japan and Chiang Mai, Thailand.

Authors:  K Sunagawa; W Sirirungsi; I Nakazato; T Hirayasu; T Iwamasa
Journal:  Int J Exp Pathol       Date:  1995-08       Impact factor: 1.925

8.  Infection of neurons and encephalitis after intracranial inoculation of herpes simplex virus requires the entry receptor nectin-1.

Authors:  Sarah J Kopp; Ghazal Banisadr; Kelly Glajch; Ulrike E Maurer; Kay Grünewald; Richard J Miller; Pavel Osten; Patricia G Spear
Journal:  Proc Natl Acad Sci U S A       Date:  2009-10-05       Impact factor: 11.205

9.  The consequences of parasitic infection for the behavior of the mammalian host.

Authors:  P J Donovick; R G Burright
Journal:  Environ Health Perspect       Date:  1987-08       Impact factor: 9.031
  9 in total

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