Photothermal generation of programmable microbubble array on nanoporous gold disks.

We present a novel technique to generate microbubbles photothermally by continuous-wave laser irradiation of nanoporous gold disk (NPGD) array covered microfluidic channels. When a single laser spot is focused on the NPGDs, a microbubble can be generated with controlled size by adjusting the laser power. The dynamics of both bubble growth and shrinkage are studied. Using computer-generated holography on a spatial light modulator (SLM), simultaneous generation of multiple microbubbles at arbitrary locations with independent control is demonstrated. A potential application of flow manipulation is demonstrated using a microfluidic X-shaped junction. The advantages of this technique are flexible bubble generation locations, long bubble lifetimes, no need for light-adsorbing dyes, high controllability over bubble size, and relatively lower power consumption.