Literature DB >> 30118723

Challenges and innovations of delivering medicines to older adults.

Danijela Gnjidic1, Andy Husband2, Adam Todd2.   

Abstract

Older adults with multimorbidity, polypharmacy, and complex health needs are the major consumer of health care. Ensuring that medicines are used safely, effectively, and delivered efficiently in this population is challenging. In this context, the approach to medicines delivery should seek to overcome some of the difficulties of delivering medicines to older people, and ensure each medication is delivered by the optimal and most convenient route for the patient in question. However, this poses significant obstacles, as the development of medicines suitable for use in older populations does not often account for complex health needs, potential challenges in relation to drug disposition, safety of excipients and limitations with practical usability of dosage forms. The objective of this review is to summarise and discuss current challenges and novel approaches to delivering medications to older adults.
Copyright © 2018. Published by Elsevier B.V.

Entities:  

Keywords:  Delivery; Geriatric pharmacology; Medicines; Older people

Mesh:

Substances:

Year:  2018        PMID: 30118723     DOI: 10.1016/j.addr.2018.08.003

Source DB:  PubMed          Journal:  Adv Drug Deliv Rev        ISSN: 0169-409X            Impact factor:   15.470


  3 in total

1.  Interventions to address potentially inappropriate prescriptions and over-the-counter medication use among adults 65 years and older in primary care settings: protocol for a systematic review.

Authors:  Andrew Beck; Navindra Persaud; Laure A Tessier; Roland Grad; Michael R Kidd; Scott Klarenbach; Christina Korownyk; Ainsley Moore; Brett D Thombs; Dee Mangin; Rita K McCracken; Emily G McDonald; Caroline Sirois; Salmaan Kanji; Frank Molnar; Stuart G Nicholls; Kednapa Thavorn; Alexandria Bennett; Nicole Shaver; Becky Skidmore; Bradley R Mitchelmore; Marc Avey; Elizabeth Rolland-Harris; Julian Little; David Moher
Journal:  Syst Rev       Date:  2022-10-20

Review 2.  Pharmacological Interactions in the Elderly.

Authors:  Emilia Błeszyńska; Łukasz Wierucki; Tomasz Zdrojewski; Marcin Renke
Journal:  Medicina (Kaunas)       Date:  2020-06-28       Impact factor: 2.430

Review 3.  Patient Centric Pharmaceutical Drug Product Design-The Impact on Medication Adherence.

Authors:  Enrica Menditto; Valentina Orlando; Giuseppe De Rosa; Paola Minghetti; Umberto Maria Musazzi; Caitriona Cahir; Marta Kurczewska-Michalak; Przemysław Kardas; Elísio Costa; José Manuel Sousa Lobo; Isabel F Almeida
Journal:  Pharmaceutics       Date:  2020-01-03       Impact factor: 6.321

  3 in total

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