| Literature DB >> 30118214 |
Zhenzhen Tian1, Juanjuan Li1, Shumiao Zhang1, Zhishan Xu1,2, Yuliang Yang1, Deliang Kong1, Hairong Zhang1, Xingxing Ge1, Junming Zhang1, Zhe Liu1.
Abstract
Poor selectivity between cancer cells and normal cells is one of the major limitations of cancer chemotherapy. Lysosome-targeted ruthenium-based complexes target tumor cells selectively, only displaying rather weak cytotoxicity or inactivity toward normal cells. Confocal microscopy was employed for the first time to determine the cellular localization of the half-sandwich Ru complex.Entities:
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Year: 2018 PMID： 30118214 DOI： 10.1021/acs.inorgchem.8b01944
Source DB: PubMed Journal: Inorg Chem ISSN： 0020-1669 Impact factor: 5.165