| Literature DB >> 3011769 |
M Kito, H Narita, H Takamura, H J Park, T Matsuura, K Tanaka.
Abstract
The early breakdown of phosphatidylinositol 4,5-bisphosphate in human platelets stimulated by a threshold concentration of either collagen or thrombin was inhibited by 5 mM NaF through its inhibition of phospholipase C activity. However, 5 mM NaF did not inhibit Ca2+ mobilization due to the stimuli from internal stores, but it did inhibit the influx of extracellular Ca2+ through its suppression of thromboxane A2 formation.Entities:
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Year: 1986 PMID： 3011769 DOI： 10.1093/oxfordjournals.jbchem.a135592
Source DB: PubMed Journal: J Biochem ISSN： 0021-924X Impact factor: 3.387