| Literature DB >> 30117000 |
P O Figueiredo1, A T S Silva2, J S Oliveira2, P E Marinho2, F T Rocha3, G P Domingos3, P C P Poblete4, L B S Oliveira5, D C Duarte4, C A Bonjardim2, J S Abrahão2, E G Kroon2, B P Drumond2, D B Oliveira3, G S Trindade6.
Abstract
At the end of 2016, Brazil experienced an unprecedented yellow fever (YF) outbreak. Clinical, molecular and ecological aspects of human and non-human primate (NHP) samples collected at the beginning of the outbreak are described in this study. Spatial distribution analyses demonstrated a strong overlap between human and NHP cases. Through molecular analyses, we showed that the outbreak had a sylvatic origin, caused by the South American genotype 1 YFV, which has already been shown to circulate in Brazil. As expected, the clusters of cases were identified in regions with a low vaccination coverage. Our findings highlight the importance of the synchronization of animal surveillance and health services to identify emerging YF cases, thereby promoting a better response to the vulnerable population.Entities:
Keywords: Arboviruses; Emerging infectious diseases; Non-human primates; Outbreak; Yellow fever virus; Zoonotic virus
Mesh：
Year: 2018 PMID： 30117000 DOI： 10.1007/s10393-018-1364-z
Source DB: PubMed Journal: Ecohealth ISSN： 1612-9202 Impact factor: 3.184