Literature DB >> 3011648

The genes for human gastrin and cholecystokinin are located on different chromosomes.

T Lund, A H Geurts van Kessel, S Haun, J E Dixon.   

Abstract

The polypeptide hormones gastrin and cholecystokinin are structurally related, having the identical pentapeptide GWMDF located at their C-terminus. The precursors to these two hormones also show amino acid homology, suggesting that they may have a common ancestral origin. Recombinant DNA clones corresponding to gene fragments encoding human gastrin and cholecystokinin were used to determine their respective chromosomal localization by analyzing human-rodent cell lines. We have assigned the cholecystokinin gene to human chromosome 3q12-3pter and the gastrin gene to chromosome 17q.

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Year:  1986        PMID: 3011648     DOI: 10.1007/bf00292669

Source DB:  PubMed          Journal:  Hum Genet        ISSN: 0340-6717            Impact factor:   4.132


  19 in total

1.  Primary structural comparison of the preprohormones cholecystokinin and gastrin.

Authors:  R J Deschenes; S V Narayana; P Argos; J E Dixon
Journal:  FEBS Lett       Date:  1985-03-11       Impact factor: 4.124

2.  Hormone production by cultures of small-cell carcinoma of the lung.

Authors:  G D Sorenson; O S Pettengill; T Brinck-Johnsen; C C Cate; L H Maurer
Journal:  Cancer       Date:  1981-03-15       Impact factor: 6.860

3.  Localization of a gene controlling the expression of the human transferrin receptor to the region q12 leads to qter of chromosome 3.

Authors:  M van de Rijn; A H Geurts van Kessel; V Kroezen; A J van Agthoven; K Verstijnen; C Terhorst; J Hilgers
Journal:  Cytogenet Cell Genet       Date:  1983

4.  Evidence for a common evolutionary origin of gastrin and cholecystokinin.

Authors:  L I Larsson; J F Rehfeld
Journal:  Nature       Date:  1977-09-22       Impact factor: 49.962

5.  A gene encoding rat cholecystokinin. Isolation, nucleotide sequence, and promoter activity.

Authors:  R J Deschenes; R S Haun; C L Funckes; J E Dixon
Journal:  J Biol Chem       Date:  1985-01-25       Impact factor: 5.157

6.  Expression of human myeloid-associated surface antigens in human-mouse myeloid cell hybrids.

Authors:  A H Geurts van Kessel; P A Tetteroo; A E von dem Borne; A Hagemeijer; D Bootsma
Journal:  Proc Natl Acad Sci U S A       Date:  1983-06       Impact factor: 11.205

7.  Structural analysis of the gene encoding human gastrin: the large intron contains an Alu sequence.

Authors:  R Ito; K Sato; T Helmer; G Jay; K Agarwal
Journal:  Proc Natl Acad Sci U S A       Date:  1984-08       Impact factor: 11.205

8.  A nonrandom chromosomal abnormality, del 3p(14-23), in human small cell lung cancer (SCLC).

Authors:  J Whang-Peng; P A Bunn; C S Kao-Shan; E C Lee; D N Carney; A Gazdar; J D Minna
Journal:  Cancer Genet Cytogenet       Date:  1982-06

Review 9.  Four basic characteristics of the gastrin-cholecystokinin system.

Authors:  J F Rehfeld
Journal:  Am J Physiol       Date:  1981-04

10.  Specific chromosome defect associated with human small-cell lung cancer; deletion 3p(14-23).

Authors:  J Whang-Peng; C S Kao-Shan; E C Lee; P A Bunn; D N Carney; A F Gazdar; J D Minna
Journal:  Science       Date:  1982-01-08       Impact factor: 47.728

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  2 in total

Review 1.  Mouse chromosome 9.

Authors:  D M Kingsley
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

2.  A network map of the gastrin signaling pathway.

Authors:  Yashwanth Subbannayya; Kumari Anuja; Jayshree Advani; Urmesh Kumar Ojha; Vishalakshi Nanjappa; Bijesh George; Avinash Sonawane; Rekha V Kumar; Girija Ramaswamy; Akhilesh Pandey; B L Somani; Rajesh Raju
Journal:  J Cell Commun Signal       Date:  2014-03-02       Impact factor: 5.782

  2 in total

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