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Literature DB >> 3011644

Characteristics and distribution of beta thalassemia haplotypes in South China.

V Chan, T K Chan, M Y Cheng, N K Leung, Y W Kan, D Todd.

Abstract

Eleven restriction site polymorphisms in the beta-globin gene cluster were determined in 48 Chinese with homozygous beta-thalassemia and their parents. Seven haplotypes were identified as associated with the beta thal chromosome and 25 with the beta A chromosome. The distribution of the various beta thal haplotypes in different regions of South China was mapped and discussed in relation to prenatal diagnosis and migration of the Chinese people.

Entities: Disease Species

Mesh：

Substances：

Year: 1986 PMID： 3011644 DOI： 10.1007/bf00292658

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

17 in total

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Journal: Trans R Soc Trop Med Hyg Date: 1964-11 Impact factor: 2.184

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Journal: Trans R Soc Trop Med Hyg Date: 1971 Impact factor: 2.184

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Authors: S H Orkin; H H Kazazian; S E Antonarakis; S C Goff; C D Boehm; J P Sexton; P G Waber; P J Giardina
Journal: Nature Date: 1982-04-15 Impact factor: 49.962

4. Quantification of the close association between DNA haplotypes and specific beta-thalassaemia mutations in Mediterraneans.

Authors: H H Kazazian; S H Orkin; A F Markham; C R Chapman; H Youssoufian; P G Waber
Journal: Nature Date: 1984 Jul 12-18 Impact factor: 49.962

5. Prenatal diagnosis of beta-thalassemia. Detection of a single nucleotide mutation in DNA.

Authors: M Pirastu; Y W Kan; A Cao; B J Conner; R L Teplitz; R B Wallace
Journal: N Engl J Med Date: 1983-08-04 Impact factor: 91.245

6. Prenatal diagnosis of beta-thalassemias by amniocentesis: linkage analysis using multiple polymorphic restriction endonuclease sites.

Authors: H H Kazazian; J A Phillips; C D Boehm; T A Vik; M J Mahoney; A K Ritchey
Journal: Blood Date: 1980-11 Impact factor: 22.113

7. Direct detection of the common Mediterranean beta-thalassemia gene with synthetic DNA probes. An alternative approach for prenatal diagnosis.

Authors: S H Orkin; A F Markham; H H Kazazian
Journal: J Clin Invest Date: 1983-03 Impact factor: 14.808

8. beta-Thalassemia in Chinese: use of in vivo RNA analysis and oligonucleotide hybridization in systematic characterization of molecular defects.

Authors: T C Cheng; S H Orkin; S E Antonarakis; M J Potter; J P Sexton; A F Markham; P J Giardina; A Li; H H Kazazian
Journal: Proc Natl Acad Sci U S A Date: 1984-05 Impact factor: 11.205

9. ATA box transcription mutation in beta-thalassemia.

Authors: S H Orkin; J P Sexton; T C Cheng; S C Goff; P J Giardina; J I Lee; H H Kazazian
Journal: Nucleic Acids Res Date: 1983-07-25 Impact factor: 16.971

10. Molecular characterization of seven beta-thalassemia mutations in Asian Indians.

Authors: H H Kazazian; S H Orkin; S E Antonarakis; J P Sexton; C D Boehm; S C Goff; P G Waber
Journal: EMBO J Date: 1984-03 Impact factor: 11.598

13 in total

1. Beta-thalassemia major resulting from a compound heterozygosity for the beta-globin gene mutation: further evidence for multiple origin and migration of the thalassemia gene.

Authors: Y Chifu; H Nakashima; H Hara; E Yokota; T Imamura
Journal: Hum Genet Date: 1992-05 Impact factor: 4.132

2. Beta-globin gene cluster haplotypes in Yanomama Indians from the Amazon region of Brazil.

Authors: J F Guerreiro; M S Figueiredo; S E Santos; M A Zago
Journal: Hum Genet Date: 1992-08 Impact factor: 4.132

3. The same beta-globin gene mutation is present on nine different beta-thalassemia chromosomes in a Sardinian population.

Authors: M Pirastu; R Galanello; M A Doherty; T Tuveri; A Cao; Y W Kan
Journal: Proc Natl Acad Sci U S A Date: 1987-05 Impact factor: 11.205

4. Molecular basis of beta thalassemia in south China. Strategy for DNA analysis.

Authors: J Z Zhang; S P Cai; X He; H X Lin; H J Lin; Z G Huang; F F Chehab; Y W Kan
Journal: Hum Genet Date: 1988-01 Impact factor: 4.132

5. Restriction fragment length polymorphisms associated with factor VIII:C gene in Chinese.

Authors: V Chan; T K Chan; V W Liu; A C Wong
Journal: Hum Genet Date: 1988-06 Impact factor: 4.132

6. Characteristics of beta A chromosome haplotypes in Japanese.

Authors: K Shimizu
Journal: Biochem Genet Date: 1987-04 Impact factor: 1.890

7. Distribution of beta-thalassemia mutations in south China and their association with haplotypes.

Authors: V Chan; T K Chan; F F Chebab; D Todd
Journal: Am J Hum Genet Date: 1987-10 Impact factor: 11.025

8. Polymorphism of the beta-globin region in apes: implications for the origin of human haplotypes.

Authors: V Vincek; R Bontrop; C O'Huigin; F Figueroa
Journal: Mamm Genome Date: 1994-06 Impact factor: 2.957

Review 9. Why are some genetic diseases common? Distinguishing selection from other processes by molecular analysis of globin gene variants.

Authors: J Flint; R M Harding; J B Clegg; A J Boyce
Journal: Hum Genet Date: 1993-03 Impact factor: 4.132

10. Evidence of gene conversion in the evolutionary process of the codon 41/42 (-CTTT) mutation causing beta-thalassemia in southern China.

Authors: Wen Zhang; Wang-Wei Cai; Wei-Ping Zhou; Hai-Peng Li; Liang Li; Wei Yan; Qin-Kai Deng; Ya-Ping Zhang; Yun-Xin Fu; Xiang-Min Xu
Journal: J Mol Evol Date: 2008-04-15 Impact factor: 2.395