Literature DB >> 30115971

Mutant NRAS Q61K is responsible for MAPK pathway activation in the MARIMO cell line and renders these cells independent of the CALR-MPL-JAK2-STAT5 pathway.

Lijuan Han1, Julia Czech1, Angela Maurer1, Tim H Brümmendorf1, Nicolas Chatain1, Steffen Koschmieder2.   

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Year:  2018        PMID： 30115971     DOI： 10.1038/s41375-018-0234-6

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  5 in total

1.  Knock-in of murine Calr del52 induces essential thrombocythemia with slow-rising dominance in mice and reveals key role of Calr exon 9 in cardiac development.

Authors:  Thomas Balligand; Younes Achouri; Christian Pecquet; Gilles Gaudray; Didier Colau; Eva Hug; Yacine Rahmani; Vincent Stroobant; Isabelle Plo; William Vainchenker; Robert Kralovics; Benoît J Van den Eynde; Jean-Philippe Defour; Stefan N Constantinescu
Journal:  Leukemia       Date:  2019-08-30       Impact factor: 11.528

Review 2.  The effects of mutant Ras proteins on the cell signalome.

Authors:  Tamás Takács; Gyöngyi Kudlik; Anita Kurilla; Bálint Szeder; László Buday; Virag Vas
Journal:  Cancer Metastasis Rev       Date:  2020-12       Impact factor: 9.264

3.  Predicting osimertinib-treatment outcomes through EGFR mutant-fraction monitoring in the circulating tumor DNA of EGFR T790M-positive patients with non-small cell lung cancer (WJOG8815L).

Authors:  Kazuko Sakai; Takayuki Takahama; Mototsugu Shimokawa; Koichi Azuma; Masayuki Takeda; Terufumi Kato; Haruko Daga; Isamu Okamoto; Hiroaki Akamatsu; Shunsuke Teraoka; Akira Ono; Tatsuo Ohira; Toshihide Yokoyama; Nobuyuki Yamamoto; Kazuhiko Nakagawa; Kazuto Nishio
Journal:  Mol Oncol       Date:  2020-11-17       Impact factor: 6.603

4.  CALR frameshift mutations in MPN patient-derived iPSCs accelerate maturation of megakaryocytes.

Authors:  Kathrin Olschok; Lijuan Han; Marcelo A S de Toledo; Janik Böhnke; Martin Graßhoff; Ivan G Costa; Alexandre Theocharides; Angela Maurer; Herdit M Schüler; Eva Miriam Buhl; Kristina Pannen; Julian Baumeister; Milena Kalmer; Siddharth Gupta; Peter Boor; Deniz Gezer; Tim H Brümmendorf; Martin Zenke; Nicolas Chatain; Steffen Koschmieder
Journal:  Stem Cell Reports       Date:  2021-10-21       Impact factor: 7.765

5.  Targeting human CALR-mutated MPN progenitors with a neoepitope-directed monoclonal antibody.

Authors:  Denis Tvorogov; Chloe A L Thompson-Peach; Johannes Foßelteder; Mara Dottore; Frank Stomski; Suraiya A Onnesha; Kelly Lim; Paul A B Moretti; Stuart M Pitson; David M Ross; Andreas Reinisch; Daniel Thomas; Angel F Lopez
Journal:  EMBO Rep       Date:  2022-02-14       Impact factor: 8.807
  5 in total

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