Literature DB >> 30112292

Disulfiram combats cancer via crippling valosin-containing protein/p97 segregase adaptor NPL4.

Nan Ding1,2, Qianzheng Zhu2,3.   

Abstract

Entities:  

Year:  2018        PMID： 30112292      PMCID： PMC6089232          DOI： 10.21037/tcr.2018.03.33

Source DB:  PubMed          Journal:  Transl Cancer Res        ISSN： 2218-676X            Impact factor:   1.241


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  25 in total

1.  A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases.

Authors:  Kyota Fujita; Yoko Nakamura; Tsutomu Oka; Hikaru Ito; Takuya Tamura; Kazuhiko Tagawa; Toshikazu Sasabe; Asuka Katsuta; Kazumi Motoki; Hiroki Shiwaku; Masaki Sone; Chisato Yoshida; Masahisa Katsuno; Yoshinobu Eishi; Miho Murata; J Paul Taylor; Erich E Wanker; Kazuteru Kono; Satoshi Tashiro; Gen Sobue; Albert R La Spada; Hitoshi Okazawa
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

2.  p97 Promotes a Conserved Mechanism of Helicase Unloading during DNA Cross-Link Repair.

Authors:  George Fullbright; Halley B Rycenga; Jordon D Gruber; David T Long
Journal:  Mol Cell Biol       Date:  2016-11-14       Impact factor: 4.272

3.  Analysis of Npl4 deletion mutants in mammalian cells unravels new Ufd1-interacting motifs and suggests a regulatory role of Npl4 in ERAD.

Authors:  Agnieszka Lass; Elizabeth McConnell; Krista Fleck; Alla Palamarchuk; Cezary Wójcik
Journal:  Exp Cell Res       Date:  2008-06-14       Impact factor: 3.905

4.  High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth.

Authors:  Kristiina Iljin; Kirsi Ketola; Paula Vainio; Pasi Halonen; Pekka Kohonen; Vidal Fey; Roland C Grafström; Merja Perälä; Olli Kallioniemi
Journal:  Clin Cancer Res       Date:  2009-09-29       Impact factor: 12.531

Review 5.  A review of the pharmacokinetics and pharmacodynamics of disulfiram and its metabolites.

Authors:  B Johansson
Journal:  Acta Psychiatr Scand Suppl       Date:  1992

6.  Sodium dithiocarb as adjuvant immunotherapy for high risk breast cancer: a randomized study.

Authors:  P Dufour; J M Lang; C Giron; B Duclos; P Haehnel; D Jaeck; J M Jung; F Oberling
Journal:  Biotherapy       Date:  1993

Review 7.  Disulfiram's Anticancer Activity: Evidence and Mechanisms.

Authors:  Yang Jiao; Bethany N Hannafon; Wei-Qun Ding
Journal:  Anticancer Agents Med Chem       Date:  2016       Impact factor: 2.505

Review 8.  VCP/p97-Mediated Unfolding as a Principle in Protein Homeostasis and Signaling.

Authors:  Johannes van den Boom; Hemmo Meyer
Journal:  Mol Cell       Date:  2017-11-16       Impact factor: 17.970

9.  Disulfiram when Combined with Copper Enhances the Therapeutic Effects of Temozolomide for the Treatment of Glioblastoma.

Authors:  Xueqing Lun; J Connor Wells; Natalie Grinshtein; Jennifer C King; Xiaoguang Hao; Ngoc-Ha Dang; Xiuling Wang; Ahmed Aman; David Uehling; Alessandro Datti; Jeffrey L Wrana; Jacob C Easaw; Artee Luchman; Samuel Weiss; J Gregory Cairncross; David R Kaplan; Stephen M Robbins; Donna L Senger
Journal:  Clin Cancer Res       Date:  2016-03-22       Impact factor: 12.531

10.  UV-induced proteolysis of RNA polymerase II is mediated by VCP/p97 segregase and timely orchestration by Cockayne syndrome B protein.

Authors:  Jinshan He; Qianzheng Zhu; Gulzar Wani; Altaf A Wani
Journal:  Oncotarget       Date:  2017-02-14
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