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Literature DB >> 3011155

Serum enzyme concentrations in untreated acute myeloid leukaemia.

C S Scott, M Davey, A Hamilton, D R Norfolk.

Abstract

Serum concentrations of lactate dehydrogenase (LDH), alpha-hydroxybutyrate dehydrogenase (HBD), phosphohexose isomerase (PHI), leucine aminopeptidase (LAP), beta-glucuronidase (beta-gluc) and angiotensin-converting enzyme (ACE), were measured in 107 cases of untreated acute myeloid leukaemia which were classified by morphological, immunological and cytochemical criteria. The results show that serum LDH was increased in most cases, irrespective of leukaemic subtype, serum PHI and LAP were significantly higher in monocytic variants and serum beta-gluc and ACE levels were generally within normal limits. In addition, significant (p less than 0.05) relationships were found between serum LDH, PHI, LAP and beta-gluc concentrations and the numbers of circulating leucocytes.

Entities: Disease Gene

Mesh：

Substances：

Year: 1986 PMID： 3011155 DOI： 10.1007/bf00320793

Source DB: PubMed Journal: Blut ISSN： 0006-5242

27 in total

1. Plasma lactic dehydrogenase and phosphohexose isomerase in leukemia.

Authors: M C BLANCHAER; P T GREEN; J P MACLEAN; M J HOLLENBERG
Journal: Blood Date: 1958-03 Impact factor: 22.113

2. The colorimetric determination of leucine aminopeptidase in urine and serum of normal subjects and patients with cancer and other diseases.

Authors: J A GOLDBARG; A M RUTENBURG
Journal: Cancer Date: 1958 Mar-Apr Impact factor: 6.860

3. Studies of the phosphoglucose isomerase of Schistosoma mansoni.

Authors: E BUEDING; J A MACKINNON
Journal: J Biol Chem Date: 1955-08 Impact factor: 5.157

4. Cytochemical, immunological and ANAE-isoenzyme studies in acute myelomonocytic leukaemia: a study of 39 cases.

Authors: C S Scott; M Morgan; H J Limbert; I D MacKarill; B E Roberts
Journal: Scand J Haematol Date: 1985-09

5. Elevated angiotensin I-converting enzyme in histiocytic medullary reticulosis.

Authors: C Grönhagen-Riska; M Klockars; O Selroos
Journal: N Engl J Med Date: 1983-02-03 Impact factor: 91.245

6. Serum lactic dehydrogenase level has prognostic value in childhood acute lymphoblastic leukemia.

Authors: C H Pui; R K Dodge; G V Dahl; G Rivera; A T Look; D Kalwinsky; W P Bowman; J Ochs; M Abromowitch; J Mirro
Journal: Blood Date: 1985-10 Impact factor: 22.113

7. Prognostic value of the determination of serum lactic dehydrogenase and its isoenzymes in children with acute lymphoblastic leukaemia.

Authors: G Hiçsönmez; K Caglar; N Renda
Journal: Scand J Haematol Date: 1985-03

Serum enzyme concentrations in untreated acute myeloid leukaemia.

1. Plasma lactic dehydrogenase and phosphohexose isomerase in leukemia.

2. The colorimetric determination of leucine aminopeptidase in urine and serum of normal subjects and patients with cancer and other diseases.

3. Studies of the phosphoglucose isomerase of Schistosoma mansoni.

4. Cytochemical, immunological and ANAE-isoenzyme studies in acute myelomonocytic leukaemia: a study of 39 cases.

5. Elevated angiotensin I-converting enzyme in histiocytic medullary reticulosis.

6. Serum lactic dehydrogenase level has prognostic value in childhood acute lymphoblastic leukemia.

7. Prognostic value of the determination of serum lactic dehydrogenase and its isoenzymes in children with acute lymphoblastic leukaemia.

8. Immune phenotype heterogeneity in AML.

9. Proposals for the classification of the acute leukaemias. French-American-British (FAB) co-operative group.

Review 10. Angiotensin-converting enzyme and its clinical significance--a review.

1. Prognostic factors and survival in chronic myelomonocytic leukaemia (CMML).