| Literature DB >> 3010929 |
H Ikram, M W Webster, M G Nicholls, G R Lewis, A M Richards, I G Crozier.
Abstract
Three cases are described of severe congestive heart failure which failed to respond to digitalis, high doses of loop diuretics, and converting-enzyme inhibitors. The addition of spironolactone produced a substantial diuresis associated with clinical and radiological improvement in each case. Although a reversible deterioration in renal function was observed, this drug combination represents a therapeutic option in end-stage heart failure.Entities:
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Year: 1986 PMID： 3010929 DOI： 10.1111/j.1445-5994.1986.tb01119.x
Source DB: PubMed Journal: Aust N Z J Med ISSN： 0004-8291