Literature DB >> 30108885

What is medicinal chemistry? - Demystifying a rapidly evolving discipline!

Selina Y L Holbrook1, Sylvie Garneau-Tsodikova1.   

Abstract

Medicinal chemistry is a scientific discipline that has progressed rapidly over the last few decades. Facilitated by the technological advancement, the early understanding of medicinal chemistry as "synthesizing bioactive molecules" has become the connecting bridge of a variety of related scientific disciplines. This opinion article will guide you through a brief evolution of this discipline and discuss what medicinal chemistry has evolved to be in this era.

Year:  2017        PMID： 30108885      PMCID： PMC6084239          DOI： 10.1039/c7md90030a

Source DB:  PubMed          Journal:  Medchemcomm        ISSN： 2040-2503            Impact factor:   3.597


  4 in total

1.  Medicine at the court of Louis XIV.

Authors:  L BERNARD
Journal:  Med Hist       Date:  1962-07       Impact factor: 1.419

2.  Rapid computational identification of the targets of protein kinase inhibitors.

Authors:  William M Rockey; Adrian H Elcock
Journal:  J Med Chem       Date:  2005-06-16       Impact factor: 7.446

3.  [History of opium poppy and morphine].

Authors:  Svend Norn; Poul R Kruse; Edith Kruse
Journal:  Dan Medicinhist Arbog       Date:  2005

4.  A high-throughput screen to identify inhibitors of ATP homeostasis in non-replicating Mycobacterium tuberculosis.

Authors:  Puiying A Mak; Srinivasa P S Rao; Mai Ping Tan; Xiuhua Lin; Jason Chyba; Joann Tay; Seow Hwee Ng; Bee Huat Tan; Joseph Cherian; Jeyaraj Duraiswamy; Pablo Bifani; Vivian Lim; Boon Heng Lee; Ngai Ling Ma; David Beer; Pamela Thayalan; Kelli Kuhen; Arnab Chatterjee; Frantisek Supek; Richard Glynne; Jun Zheng; Helena I Boshoff; Clifton E Barry; Thomas Dick; Kevin Pethe; Luis R Camacho
Journal:  ACS Chem Biol       Date:  2012-04-25       Impact factor: 5.100
  4 in total

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