Literature DB >> 30108348

Gene-silencing technology gets first drug approval after 20-year wait.

Heidi Ledford.   

Abstract

Keywords:  Drug discovery; Gene therapy; Medical research

Mesh:

Substances:

Year:  2018        PMID: 30108348     DOI: 10.1038/d41586-018-05867-7

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


× No keyword cloud information.
  34 in total

Review 1.  Leading RNA Interference Therapeutics Part 1: Silencing Hereditary Transthyretin Amyloidosis, with a Focus on Patisiran.

Authors:  Simoneide S Titze-de-Almeida; Pedro Renato de Paula Brandão; Ingrid Faber; Ricardo Titze-de-Almeida
Journal:  Mol Diagn Ther       Date:  2020-02       Impact factor: 4.074

Review 2.  siRNA therapeutics for breast cancer: recent efforts in targeting metastasis, drug resistance, and immune evasion.

Authors:  Worapol Ngamcherdtrakul; Wassana Yantasee
Journal:  Transl Res       Date:  2019-08-19       Impact factor: 7.012

Review 3.  Epigenetic regulation of anterior segment diseases and potential therapeutics.

Authors:  Eric Chen; Kelley Bohm; Mark Rosenblatt; Kai Kang
Journal:  Ocul Surf       Date:  2020-04-25       Impact factor: 5.033

4.  Specificity from nonspecific interaction: regulation of tumor necrosis factor-α activity by DNA.

Authors:  Helena Andrade; Weilin Lin; Yixin Zhang
Journal:  J Biol Chem       Date:  2019-02-27       Impact factor: 5.157

Review 5.  RNA delivery biomaterials for the treatment of genetic and rare diseases.

Authors:  Weiyu Zhao; Xucheng Hou; Olivia G Vick; Yizhou Dong
Journal:  Biomaterials       Date:  2019-06-20       Impact factor: 12.479

6.  Preclinical Safety Assessment of Therapeutic Oligonucleotides.

Authors:  Patrik Andersson
Journal:  Methods Mol Biol       Date:  2022

Review 7.  Functionalized nanoparticles targeting biomarkers for prostate cancer imaging and therapy.

Authors:  Ankur U Choksi; Amir I Khan; Soum D Lokeshwar; Daniel Segal; Robert M Weiss; Darryl T Martin
Journal:  Am J Clin Exp Urol       Date:  2022-06-15

8.  Silencing VDAC1 to Treat Mesothelioma Cancer: Tumor Reprograming and Altering Tumor Hallmarks.

Authors:  Swaroop Kumar Pandey; Renen Machlof-Cohen; Manikandan Santhanam; Anna Shteinfer-Kuzmine; Varda Shoshan-Barmatz
Journal:  Biomolecules       Date:  2022-06-27

Review 9.  Mechanisms of Fibrosis Development in Nonalcoholic Steatohepatitis.

Authors:  Robert F Schwabe; Ira Tabas; Utpal B Pajvani
Journal:  Gastroenterology       Date:  2020-02-08       Impact factor: 22.682

Review 10.  Long and short non-coding RNA and radiation response: a review.

Authors:  Jared M May; Michelle Bylicky; Sunita Chopra; C Norman Coleman; Molykutty J Aryankalayil
Journal:  Transl Res       Date:  2021-02-11       Impact factor: 10.171

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.