Literature DB >> 3010694

Beta 2 receptors on myocardial cells in human ventricular myocardium.

M R Bristow, R Ginsburg.   

Abstract

Beta 2-adrenergic receptors comprise 40% of the total beta-receptor population in failing human right ventricles, as deduced from computer modeling of iodine-125 iodocyanopindolol-ICI 118,551 competition curves. A myocardial cell origin of at least some of the beta 2 subpopulation was demonstrated by documenting a beta 2-receptor mediated positive inotropic response to the selective beta 2 agonist zinterol. It is concluded that beta 2-adrenergic receptors are present on human ventricular myocardial cells.

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Year:  1986        PMID： 3010694     DOI： 10.1016/0002-9149(86)90880-5

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN： 0002-9149            Impact factor:   2.778


  14 in total

1.  Comparison of hypokalaemic, electrocardiographic and haemodynamic responses to inhaled isoprenaline and salbutamol in young and elderly subjects.

Authors:  B J Lipworth; B F Tregaskis; D G McDevitt
Journal:  Eur J Clin Pharmacol       Date:  1991       Impact factor: 2.953

2.  A dose-ranging study to evaluate the beta 1-adrenoceptor selectivity of bisoprolol.

Authors:  B J Lipworth; N A Irvine; D G McDevitt
Journal:  Eur J Clin Pharmacol       Date:  1991       Impact factor: 2.953

Review 3.  Cardiac gene therapy.

Authors:  Antoine H Chaanine; Jill Kalman; Roger J Hajjar
Journal:  Semin Thorac Cardiovasc Surg       Date:  2010

4.  The effects of chronic dosing on the beta 1 and beta 2-adrenoceptor antagonism of betaxolol and atenolol.

Authors:  B J Lipworth; N A Irvine; D G McDevitt
Journal:  Eur J Clin Pharmacol       Date:  1991       Impact factor: 2.953

5.  A Case of Congenital Complete Atrioventricular Block Treated with Transdermal Tulobuterol.

Authors:  Toshihiko Ikuta; Kazumichi Fujioka; Yumi Sato; Mariko Ashina; Sachiyo Fukushima; Shohei Ohyama; Saki Okubo; Keiji Yamana; Mayumi Morizane; Kenji Tanimura; Masashi Deguchi; Kazumoto Iijima; Ichiro Morioka; Hideto Yamada
Journal:  Kobe J Med Sci       Date:  2018-04-19

6.  Electrophysiological effects mediated by the stimulation of cardiac beta 2-adrenoceptors with tulobuterol.

Authors:  A Mugelli; S Amerini; P De Bonfioli Cavalcabo; E Cerbai; S Visentin
Journal:  Cardiovasc Drugs Ther       Date:  1987       Impact factor: 3.727

Review 7.  Selective updates on mechanisms of action of positive inotropic agents.

Authors:  G Grupp
Journal:  Mol Cell Biochem       Date:  1987-08       Impact factor: 3.396

8.  The pharmacokinetics of the beta 2-adrenoceptor agonist, tulobuterol, given transdermally and by inhalation.

Authors:  T Uematsu; M Nakano; K Kosuge; M Kanamaru; M Nakashima
Journal:  Eur J Clin Pharmacol       Date:  1993       Impact factor: 2.953

9.  Determination of infundibular innervation and amine receptor content in cyanotic and acyanotic myocardium: relation to clinical events in tetralogy of Fallot.

Authors:  L B McGrath; C Chen; J Gu; J Bianchi; J M Levett
Journal:  Pediatr Cardiol       Date:  1991-07       Impact factor: 1.655

10.  Beta 2-adrenoceptor-mediated positive inotropic effect of adrenaline in human ventricular myocardium. Quantitative discrepancies with binding and adenylate cyclase stimulation.

Authors:  A J Kaumann; H Lemoine
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1987-04       Impact factor: 3.000
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