Literature DB >> 30106596

Therapeutic Engagement of the Histone Deacetylase IIA-Myocyte Enhancer Factor 2 Axis Improves Experimental Pulmonary Hypertension.

Avraham Sofer1, Seyoung Lee1, Irinna Papangeli1, Takaomi Adachi1, Cheol Hwangbo1, Suzy Comhair2, Paul DaSilva-Jardine3, Jongmin Kim4, John J Schwarz5, Serpil C Erzurum2, Hyung J Chun1.   

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Year:  2018        PMID： 30106596      PMCID： PMC6290937          DOI： 10.1164/rccm.201805-0817LE

Source DB:  PubMed          Journal:  Am J Respir Crit Care Med        ISSN： 1073-449X            Impact factor:   21.405


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  12 in total

1.  Restoration of impaired endothelial myocyte enhancer factor 2 function rescues pulmonary arterial hypertension.

Authors:  Jongmin Kim; Cheol Hwangbo; Xiaoyue Hu; Yujung Kang; Irinna Papangeli; Devi Mehrotra; Hyekyung Park; Hyekyung Ju; Danielle L McLean; Suzy A Comhair; Serpil C Erzurum; Hyung J Chun
Journal:  Circulation       Date:  2014-10-21       Impact factor: 29.690

2.  Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension.

Authors:  L Taraseviciene-Stewart; Y Kasahara; L Alger; P Hirth; G Mc Mahon ; J Waltenberger; N F Voelkel; R M Tuder
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3.  Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis.

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Journal:  Nature       Date:  2010-05-27       Impact factor: 49.962

4.  Translational Advances in the Field of Pulmonary Hypertension. Translating MicroRNA Biology in Pulmonary Hypertension. It Will Take More Than "miR" Words.

Authors:  Hyung J Chun; Sébastien Bonnet; Stephen Y Chan
Journal:  Am J Respir Crit Care Med       Date:  2017-01-15       Impact factor: 21.405

5.  Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment.

Authors:  John T Isaacs; Lizamma Antony; Susan L Dalrymple; W Nathaniel Brennen; Stephanie Gerber; Hans Hammers; Michel Wissing; Sushant Kachhap; Jun Luo; Li Xing; Per Björk; Anders Olsson; Anders Björk; Tomas Leanderson
Journal:  Cancer Res       Date:  2012-11-13       Impact factor: 12.701

6.  Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group.

Authors:  Mercedes Lobera; Kevin P Madauss; Denise T Pohlhaus; Quentin G Wright; Mark Trocha; Darby R Schmidt; Erkan Baloglu; Ryan P Trump; Martha S Head; Glenn A Hofmann; Monique Murray-Thompson; Benjamin Schwartz; Subhas Chakravorty; Zining Wu; Palwinder K Mander; Laurens Kruidenier; Robert A Reid; William Burkhart; Brandon J Turunen; James X Rong; Craig Wagner; Mary B Moyer; Carrow Wells; Xuan Hong; John T Moore; Jon D Williams; Dulce Soler; Shomir Ghosh; Michael A Nolan
Journal:  Nat Chem Biol       Date:  2013-03-24       Impact factor: 15.040

Review 7.  MEF2: a central regulator of diverse developmental programs.

Authors:  Matthew J Potthoff; Eric N Olson
Journal:  Development       Date:  2007-10-24       Impact factor: 6.868

8.  Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development.

Authors:  Yujung Kang; Jongmin Kim; Joshua P Anderson; Jingxia Wu; Scott R Gleim; Ramendra K Kundu; Danielle L McLean; Jun-dae Kim; Hyekyung Park; Suk-won Jin; John Hwa; Thomas Quertermous; Hyung J Chun
Journal:  Circ Res       Date:  2013-04-19       Impact factor: 17.367

9.  A miR-208-Mef2 axis drives the decompensation of right ventricular function in pulmonary hypertension.

Authors:  Roxane Paulin; Gopinath Sutendra; Vikram Gurtu; Peter Dromparis; Alois Haromy; Steeve Provencher; Sebastien Bonnet; Evangelos D Michelakis
Journal:  Circ Res       Date:  2014-10-06       Impact factor: 17.367

10.  Endothelial Myocyte Enhancer Factor 2c Inhibits Migration of Smooth Muscle Cells Through Fenestrations in the Internal Elastic Lamina.

Authors:  Yao Wei Lu; Anthony M Lowery; Li-Yan Sun; Harold A Singer; Guohao Dai; Alejandro P Adam; Peter A Vincent; John J Schwarz
Journal:  Arterioscler Thromb Vasc Biol       Date:  2017-05-04       Impact factor: 8.311
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Authors:  Robert D Brown; Mehdi A Fini; Kurt R Stenmark
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Review 2.  The Search for Disease-Modifying Therapies in Pulmonary Hypertension.

Authors:  Chen-Shan Chen Woodcock; Stephen Y Chan
Journal:  J Cardiovasc Pharmacol Ther       Date:  2019-02-17       Impact factor: 2.457

3.  Regulatory T Cell-Related Gene Indicators in Pulmonary Hypertension.

Authors:  Yan Liu; Jun-Zhuo Shi; Rong Jiang; Shao-Fei Liu; Yang-Yang He; Emiel P C van der Vorst; Christian Weber; Yvonne Döring; Yi Yan
Journal:  Front Pharmacol       Date:  2022-05-31       Impact factor: 5.988

4.  MEF2 (Myocyte Enhancer Factor 2) Is Essential for Endothelial Homeostasis and the Atheroprotective Gene Expression Program.

Authors:  Yao Wei Lu; Nina Martino; Brennan D Gerlach; John M Lamar; Peter A Vincent; Alejandro P Adam; John J Schwarz
Journal:  Arterioscler Thromb Vasc Biol       Date:  2021-01-07       Impact factor: 8.311

5.  Integrative proteomics and phosphoproteomics in pulmonary arterial hypertension.

Authors:  Weiling Xu; Suzy A A Comhair; Ruoying Chen; Bo Hu; Yuan Hou; Yadi Zhou; Lori A Mavrakis; Allison J Janocha; Ling Li; Dongmei Zhang; Belinda B Willard; Kewal Asosingh; Feixiong Cheng; Serpil C Erzurum
Journal:  Sci Rep       Date:  2019-12-09       Impact factor: 4.379

6.  Isoform-specific characterization of class I histone deacetylases and their therapeutic modulation in pulmonary hypertension.

Authors:  Swati Dabral; Sobha Rani Basineni; Chien-Nien Chen; Prakash Chelladurai; Mario Schmoranzer; Nina Bender; Christine Feld; René Reiner Nötzold; Gergana Dobreva; Jochen Wilhelm; Benno Jungblut; Lan Zhao; Uta-Maria Bauer; Werner Seeger; Soni Savai Pullamsetti
Journal:  Sci Rep       Date:  2020-07-30       Impact factor: 4.379
  6 in total

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