Literature DB >> 30106543

Genetic counseling prior to Assisted Reproductive Technology procedures in the era of cytogenomics.

Roberto Coco1.   

Abstract

The possibility of sequencing hundreds of genes simultaneously and performing molecular karyotyping thanks to the introduction of novel genetic tools has expanded the use of preconception screening for blastocyst recessive mutations and aneuploidies before embryo transfer, with the ultimate purpose of increasing the proportion of normal healthy newborns. Since medically-assisted reproduction procedures are increasingly required to be eugenic, and the aforementioned genetic tests cover only half of the potential genetic diseases occurring at birth, it seems reasonable to incorporate genetic counseling in the practice of assisted reproduction to avoid prosecution for malpractice.

Entities:  

Keywords:  NGS; PGT-A; PGT-M; assisted reproductive technologies; genetic counseling; genetic testing

Year:  2018        PMID: 30106543      PMCID: PMC6210621          DOI: 10.5935/1518-0557.20180050

Source DB:  PubMed          Journal:  JBRA Assist Reprod        ISSN: 1517-5693


  14 in total

1.  Healthy Babies after Intrauterine Transfer of Mosaic Aneuploid Blastocysts.

Authors:  Ermanno Greco; Maria Giulia Minasi; Francesco Fiorentino
Journal:  N Engl J Med       Date:  2015-11-19       Impact factor: 91.245

Review 2.  Expanded carrier screening: A review of early implementation and literature.

Authors:  Gabriel A Lazarin; Imran S Haque
Journal:  Semin Perinatol       Date:  2015-12-21       Impact factor: 3.300

Review 3.  Does intracytoplasmic sperm injection pose an increased risk of genitourinary congenital malformations in offspring compared to in vitro fertilization? A systematic review and meta-analysis.

Authors:  Peter A Massaro; Dawn Lee MacLellan; Peter A Anderson; Rodrigo L P Romao
Journal:  J Urol       Date:  2015-03-24       Impact factor: 7.450

4.  The risk for four specific congenital heart defects associated with assisted reproductive techniques: a population-based evaluation.

Authors:  Karim Tararbit; Nathalie Lelong; Anne-Claire Thieulin; Lucile Houyel; Damien Bonnet; François Goffinet; Babak Khoshnood
Journal:  Hum Reprod       Date:  2012-11-22       Impact factor: 6.918

Review 5.  Are children born from singleton pregnancies conceived by ICSI at increased risk for congenital malformations when compared to children conceived naturally? A systematic review and meta-analysis.

Authors:  Celeste Lacamara; Carolina Ortega; Sonia Villa; Ricardo Pommer; Juan Enrique Schwarze
Journal:  JBRA Assist Reprod       Date:  2017-09-01

6.  Assisted reproductive technology and major birth defects in Western Australia.

Authors:  Michele Hansen; Jennifer J Kurinczuk; Nicholas de Klerk; Peter Burton; Carol Bower
Journal:  Obstet Gynecol       Date:  2012-10       Impact factor: 7.661

7.  In vitro fertilization (IVF) in Sweden: risk for congenital malformations after different IVF methods.

Authors:  Bengt Källén; Orvar Finnström; Karl Gösta Nygren; Petra Otterblad Olausson
Journal:  Birth Defects Res A Clin Mol Teratol       Date:  2005-03

8.  Committee Opinion No. 691: Carrier Screening for Genetic Conditions.

Authors: 
Journal:  Obstet Gynecol       Date:  2017-03       Impact factor: 7.661

9.  Congenital malformations in infants conceived following assisted reproductive technology in comparison with spontaneously conceived infants.

Authors:  A Farhi; B Reichman; V Boyko; S Mashiach; A Hourvitz; E J Margalioth; D Levran; I Calderon; R Orvieto; A Ellenbogen; J Meyerovitch; R Ron-El; L Lerner-Geva
Journal:  J Matern Fetal Neonatal Med       Date:  2013-03-21

10.  Preimplantation genetic screening- the required RCT that has not yet been carried out.

Authors:  Raoul Orvieto
Journal:  Reprod Biol Endocrinol       Date:  2016-06-24       Impact factor: 5.211

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.