Mohammed A Garout 1 , Hani A A Jokhdar 1 , Imad A Aljahdali 1 , Ahmed R Zein 2 , Reda A Goweda 1,3 , Abdurahman Hassan-Hussein 1 Show Affiliations »
Abstract
OBJECTIVE: The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a novel coronavirus circulating in the Arabian Peninsula since September 2012. It leads to significant respiratory disease and among patients with co-morbidities is associated with high mortality. This research studied the mortality rate of MERS-CoV among intensive care unit (ICU) patients and the correlation of mortality with different co-morbidities. METHODS: This was a retrospective observational study conducted at the Intensive Care Unit of the King Fahad Hospital, Jeddah, Saudi Arabia. Data was obtained through patient chart review. RESULTS: The total sample consisted of 52 laboratory-confirmed MERS-CoV infection patients. 39 patients died, with a 75% case-fatality rate. Many patients had underlying co-morbidities, including diabetes mellitus (51.9%), hypertension (46.2%), and chronic renal disease (21.2%). CONCLUSIONS: MERS-CoV ICU mortality remains markedly high due to a combination of factors; the disease process of MERS-CoV leads to multiple organ failure, particularly respiratory and renal failure. Copyright© by the National Institute of Public Health, Prague 2018.
OBJECTIVE: The Middle East Respiratory Syndrome Coronavirus (MERS-CoV ) is a novel coronavirus circulating in the Arabian Peninsula since September 2012. It leads to significant respiratory disease and among patients with co-morbidities is associated with high mortality. This research studied the mortality rate of MERS-CoV among intensive care unit (ICU) patients and the correlation of mortality with different co-morbidities. METHODS: This was a retrospective observational study conducted at the Intensive Care Unit of the King Fahad Hospital, Jeddah, Saudi Arabia. Data was obtained through patient chart review. RESULTS: The total sample consisted of 52 laboratory-confirmed MERS-CoV infection patients . 39 patients died, with a 75% case-fatality rate. Many patients had underlying co-morbidities, including diabetes mellitus (51.9%), hypertension (46.2%), and chronic renal disease (21.2%). CONCLUSIONS: MERS-CoV ICU mortality remains markedly high due to a combination of factors; the disease process of MERS-CoV leads to multiple organ failure , particularly respiratory and renal failure . Copyright© by the National Institute of Public Health, Prague 2018.
Entities: Disease
Species
Keywords:
Middle East Respiratory Syndrome Coronavirus; Saudi Arabia; intensive care units; mortality
Mesh： See more »
Year: 2018
PMID： 30102495 DOI： 10.21101/cejph.a4764
Source DB: PubMed Journal: Cent Eur J Public Health ISSN： 1210-7778 Impact factor: 1.163