Literature DB >> 30101416

Clinical efficacy of a chlorhexidine-based mouthrinse containing hyaluronic acid and an antidiscoloration system in patients undergoing flap surgery: A triple-blind, parallel-arm, randomized controlled trial.

Leonardo Trombelli1,2, Anna Simonelli1, Mattia Pramstraller1,2, Maria Elena Guarnelli1,2, Chiara Fabbri1,2, Elisa Maietti3, Roberto Farina1,2.   

Abstract

OBJECTIVES: To evaluate the postsurgery gingival healing as well as plaque, gingival inflammation and staining levels following the use of a 0.2% chlorhexidine (CHX) solution with or without antidiscoloration system (ADS) and 0.2% hyaluronic acid (HA).
METHODS: Patients undergoing flap surgery at sites with an intact or reduced but healthy periodontium participated in a parallel-arm RCT. After surgery, patients used the assigned mouthrinse (CHX + HA + ADS or CHX) for 21 days. At days 7 and 21, the healing process was evaluated at experimental teeth using a composite index, namely the Gingival Healing Index (GHI). GHI score was obtained as the sum of the scores related to the severity of wound dehiscence (score 1-3) and the profile of the buccal and oral aspects of the papilla (score 1-3). Therefore, GHI ranged from 2 (worst quality of healing) to 6 (optimal quality of healing). Plaque Index (PlI), Gingival Index (GI), angulated bleeding score (AngBS), and tooth and tongue staining were also assessed.
RESULTS: In both groups, GHI assumed values of 5 or 6 at both days 7 and 21 in ≥50% of patients, and low median values of PlI, GI, AngBS and staining were observed during the 21-day period. Except for a significantly lower GI in CHX group at day 7, no other significant intergroup differences were found.
CONCLUSIONS: Postsurgery plaque control based on either CHX or CHX + HA + ADS mouthrinses results in optimal plaque control and quality of early gingival healing along with limited tooth and tongue staining.
© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  chlorhexidine; gingiva; hyaluronic acid; surgical flaps; tooth discoloration; wound healing

Mesh:

Substances:

Year:  2018        PMID: 30101416     DOI: 10.1111/idh.12361

Source DB:  PubMed          Journal:  Int J Dent Hyg        ISSN: 1601-5029            Impact factor:   2.477


  3 in total

1.  Early Wound Healing Score (EHS): An Intra- and Inter-Examiner Reliability Study.

Authors:  Lorenzo Marini; Philipp Sahrmann; Mariana Andrea Rojas; Camilla Cavalcanti; Giorgio Pompa; Piero Papi; Andrea Pilloni
Journal:  Dent J (Basel)       Date:  2019-09-01

2.  Tolerability of a green tea-based mouth rinse: A pilot study.

Authors:  Renad Abdulkarim; Aliyah Al-Subhi; Renad Bukhari; Nehhal Alkhattabi; Rolla Mira; Osama Felemban; Lena Elbadawi; Soulafa Almazrooa; Hani Mawardi
Journal:  Saudi Dent J       Date:  2019-04-18

3.  Does chlorhexidine mouthwash, with an anti-discoloration system, reduce tooth surface discoloration without losing its efficacy? A systematic review and meta-analysis.

Authors:  Bregje W M Van Swaaij; G A Fridus van der Weijden; Eric W P Bakker; Filippo Graziani; Dagmar E Slot
Journal:  Int J Dent Hyg       Date:  2019-08-01       Impact factor: 2.477

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.