Fernandez Hervé1, Ardaens Katty2, Queval Isabelle3, Solignac Céline4. 1. Department of Obstetrics and Gynaecology, Bicêtre Hospital, Kremlin-Bicêtre, France. Electronic address: herve.fernandez@aphp.fr. 2. Department of Gynaecology, Residence Paul Eluard Medical Centre, Seclin, France. 3. INS HEA - Paris Lumières University, EA 7287 GRHAPES, Suresnes, France. 4. Gedeon Richter France, Medical Department, Paris, France.
Abstract
OBJECTIVE: To study clinical impact of symptomatic uterine fibroids on women's health-related perceived quality of life regarding several dimensions. STUDY DESIGN: A prospective cross-sectional web-based survey was conducted from August 18th to September 2nd 2016 among the general French population of women. A total of 1287 French women over the age of 18, among which 302 reported symptomatic uterine fibroids were surveyed. Data concerning demographics, symptoms and health-related quality of life (HRQL) using the UFS-QoL questionnaire, an overall well-being score and overall discomfort score were collected. RESULTS: Almost two thirds of surveyed women (n = 193; 64%) reported moderate to severe fibroid-related symptoms (symptom severity score between 40 and 100). The global HRQL score showed that 64% of women (n = 193) reported a moderate to very important impact of fibroids on quality of life (HRQL global score between 0 and 50). The worse HRQL scores were reported for concern (57.5 ± 26.7), energy (58.1 ± 23.2) and self-conscious subscales (63.4 ± 24.3). The mean overall well-being score was lower in women with symptomatic uterine fibroids (6.6 ± 1.7) than in women without (7.3 ± 1.5). The mean overall discomfort score rated by women with symptomatic uterine fibroid was 5.7 ± 2.5 with a score between 6 and 10 reported by 56% of them. CONCLUSIONS: We observed that 64% of surveyed women reported a moderate to very important impact of fibroids on their quality of life. This perceived alteration of quality of life together with the severity of symptomatic fibroids have a significant impact on the overall level of discomfort perceived by women and on their personal quality of life.
OBJECTIVE: To study clinical impact of symptomatic uterine fibroids on women's health-related perceived quality of life regarding several dimensions. STUDY DESIGN: A prospective cross-sectional web-based survey was conducted from August 18th to September 2nd 2016 among the general French population of women. A total of 1287 French women over the age of 18, among which 302 reported symptomatic uterine fibroids were surveyed. Data concerning demographics, symptoms and health-related quality of life (HRQL) using the UFS-QoL questionnaire, an overall well-being score and overall discomfort score were collected. RESULTS: Almost two thirds of surveyed women (n = 193; 64%) reported moderate to severe fibroid-related symptoms (symptom severity score between 40 and 100). The global HRQL score showed that 64% of women (n = 193) reported a moderate to very important impact of fibroids on quality of life (HRQL global score between 0 and 50). The worse HRQL scores were reported for concern (57.5 ± 26.7), energy (58.1 ± 23.2) and self-conscious subscales (63.4 ± 24.3). The mean overall well-being score was lower in women with symptomatic uterine fibroids (6.6 ± 1.7) than in women without (7.3 ± 1.5). The mean overall discomfort score rated by women with symptomatic uterine fibroid was 5.7 ± 2.5 with a score between 6 and 10 reported by 56% of them. CONCLUSIONS: We observed that 64% of surveyed women reported a moderate to very important impact of fibroids on their quality of life. This perceived alteration of quality of life together with the severity of symptomatic fibroids have a significant impact on the overall level of discomfort perceived by women and on their personal quality of life.
Authors: Mei-An Middelkoop; Maria E de Lange; T Justin Clark; Ben Willem J Mol; Pierre M Bet; Judith A F Huirne; Wouter J K Hehenkamp Journal: Hum Reprod Date: 2022-05-03 Impact factor: 6.353
Authors: Michał Ciebiera; Marta Włodarczyk; Stanisław Zgliczyński; Tomasz Łoziński; Klaudia Walczak; Artur Czekierdowski Journal: Int J Mol Sci Date: 2020-04-24 Impact factor: 5.923
Authors: Manuela Neri; Gian Benedetto Melis; Elena Giancane; Valerio Vallerino; Monica Pilloni; Bruno Piras; Alessandro Loddo; Anna Maria Paoletti; Valerio Mais Journal: Int J Womens Health Date: 2019-10-22
Authors: Kedra Wallace; Elizabeth A Stewart; Lauren A Wise; Wanda Kay Nicholson; John Preston Parry; Shuaiqi Zhang; Shannon Laughlin-Tommaso; Vanessa Jacoby; Raymond M Anchan; Michael P Diamond; Sateria Venable; Amber Shiflett; Ganesa R Wegienka; George Larry Maxwell; Daniel Wojdyla; Evan R Myers; Erica Marsh Journal: J Womens Health (Larchmt) Date: 2021-06-08 Impact factor: 2.681