Nik M N Nik Zuraina1, Abdullah Sarimah2, Mohamad Suharni3, Habsah Hasan1, Siti Suraiya4. 1. Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia. 2. Biostatistics and Research Methodology Unit, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia. 3. School of Dental Sciences, Universiti Sains Malaysia, Kelantan, Malaysia. 4. Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia. Electronic address: ssuraiya@usm.my.
Abstract
BACKGROUND: Overcrowding during the annual Hajj pilgrimage has been known to increase the risk of infectious diseases transmission. Despite the high prevalence of respiratory illness among Malaysian Hajj pilgrims, knowledge about the etiologic pathogens is yet very limited. Thus, this study aimed to determine the spectrum of bacterial respiratory pathogens among the Hajj pilgrims returning to Malaysia in year 2016. METHODS: Expectorated sputum specimens were collected from the Hajj pilgrims with symptomatic respiratory tract infections (RTIs). Subsequently, the bacterial pathogens were identified using the standard bacteriological culture method and Vitek II system. RESULTS: This study indicated that 255 (87.33%) out of 292 cultured sputa were positive with at least one potential pathogenic bacteria. Out of 345 total bacterial isolates, 60% (n=207) were Haemophilus influenzae, which was associated with both single bacterium infection (132/173, 76.3%) and multiple bacterial infections (75/82, 91.5%). The other bacterial isolates included; Klebsiella pneumoniae (n=37, 10.7%), Moraxella catarrhalis (n=27, 7.8%), Haemophilus parainfluenzae (n=25, 7.2%), Streptococcus group G (n=18, 5.2%), Klebsiella spesies (n=16, 4.6%), Streptococcus pneumoniae (n=11, 3.2%) and few other organisms. CONCLUSION: High frequency of H. influenzae was isolated from Malaysian Hajj pilgrims, especially those with respiratory symptoms. Further study should evaluate the actual pathogenicity of the organism and the interactions between the respiratory microbiota towards developing effective prevention strategies of RTIs among the local pilgrims.
BACKGROUND: Overcrowding during the annual Hajj pilgrimage has been known to increase the risk of infectious diseases transmission. Despite the high prevalence of respiratory illness among Malaysian Hajj pilgrims, knowledge about the etiologic pathogens is yet very limited. Thus, this study aimed to determine the spectrum of bacterial respiratory pathogens among the Hajj pilgrims returning to Malaysia in year 2016. METHODS: Expectorated sputum specimens were collected from the Hajj pilgrims with symptomatic respiratory tract infections (RTIs). Subsequently, the bacterial pathogens were identified using the standard bacteriological culture method and Vitek II system. RESULTS: This study indicated that 255 (87.33%) out of 292 cultured sputa were positive with at least one potential pathogenic bacteria. Out of 345 total bacterial isolates, 60% (n=207) were Haemophilus influenzae, which was associated with both single bacterium infection (132/173, 76.3%) and multiple bacterial infections (75/82, 91.5%). The other bacterial isolates included; Klebsiella pneumoniae (n=37, 10.7%), Moraxella catarrhalis (n=27, 7.8%), Haemophilus parainfluenzae (n=25, 7.2%), Streptococcus group G (n=18, 5.2%), Klebsiella spesies (n=16, 4.6%), Streptococcus pneumoniae (n=11, 3.2%) and few other organisms. CONCLUSION: High frequency of H. influenzae was isolated from Malaysian Hajj pilgrims, especially those with respiratory symptoms. Further study should evaluate the actual pathogenicity of the organism and the interactions between the respiratory microbiota towards developing effective prevention strategies of RTIs among the local pilgrims.
Authors: Hamid Bokhary; Hajj Research Team; Osamah Barasheed; Hala B Othman; Burhanudin Saha; Harunor Rashid; Grant A Hill-Cawthorne; Moataz Abd El Ghany Journal: Access Microbiol Date: 2022-04-25
Authors: Mohammed Dauda Goni; Nyi Nyi Naing; Habsah Hasan; Nadiah Wan-Arfah; Zakuan Zainy Deris; Wan Nor Arifin; Aisha Abubakar Baaba; Babagana Mohammed Adam; Muhammad Rafie Arshad Journal: Front Public Health Date: 2021-07-01
Authors: Mohammed Dauda Goni; Habsah Hasan; Nadiah Wan-Arfah; Nyi Nyi Naing; Zakuan Zainy Deris; Wan Nor Arifin; Aisha Abubakar Baaba; Abdulwahab Aliyu; Babagana Mohammed Adam Journal: Front Public Health Date: 2020-09-03
Authors: Mohammed Dauda Goni; Habsah Hasan; Nyi Nyi Naing; Nadiah Wan-Arfah; Zakuan Zeiny Deris; Wan Nor Arifin; Aisha Abubakar Baaba Journal: Int J Environ Res Public Health Date: 2019-11-18 Impact factor: 3.390