Bobby Tingstedt1, Bodil Andersson2, Claes Jönsson3, Victoria Formichov4, Svein-Olav Bratlie3, Mikael Öhman5, Britt-Marie Karlsson6, Christophe Ansorge7, Ralf Segersvärd7, Thomas Gasslander8. 1. Department of Surgery, Skåne University Hospital, Lund, Sweden. Electronic address: bobby.tingstedt@med.lu.se. 2. Department of Surgery, Skåne University Hospital, Lund, Sweden. 3. Department of Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden. 4. Southeast Regional Cancer Centre, Linköping, Sweden. 5. Departments of Surgical and Perioperative Sciences, Umeå University Hospital, Sweden. 6. Department Surgery, Uppsala University Hospital, Sweden. 7. Department of Surgical Gastroenterology, Karolinska University Hospital, Stockholm, Sweden. 8. Department of Surgery, Linköping University Hospital, Sweden.
Abstract
BACKGROUND: Despite improvements in therapy regimens over the past decades, overall survival rates for pancreatic and periampullary cancer are poor. Specific cancer registries are set up in various nations to regional differences and to enable larger prospective trials. The aim of this study was to describe the Swedish register, including possibilities to improve diagnostic work-ups, treatment, and follow-up by means of the register. METHODS: Since 2010, all patients with pancreatic and periampullary cancer (including also patients who have undergone pancreatic surgery due to premalignant or benign lesions) have been registered in the Swedish National Periampullary and Pancreatic Cancer registry. RESULTS: In total 9887 patients are listed in the registry; 8207 of those have malignant periampullary cancer. Approximately one-third (3282 patients) have had resections performed, including benign/premalignant resections. 30-day and 90-day mortality after pancreatoduodenectomy is 1.5% and 3.5%, respectively. The overall 3-year survival for resected pancreatic ductal adenocarcinoma is 35%. Regional variations decreased over the studied period, but still exist. CONCLUSION: Results from the Swedish National Registry are satisfactory and comparable to international standards. Trends over time show increasing resection rates and some improved results. Better collaboration and openness within pancreatic surgeons is an important side effect.
BACKGROUND: Despite improvements in therapy regimens over the past decades, overall survival rates for pancreatic and periampullary cancer are poor. Specific cancer registries are set up in various nations to regional differences and to enable larger prospective trials. The aim of this study was to describe the Swedish register, including possibilities to improve diagnostic work-ups, treatment, and follow-up by means of the register. METHODS: Since 2010, all patients with pancreatic and periampullary cancer (including also patients who have undergone pancreatic surgery due to premalignant or benign lesions) have been registered in the Swedish National Periampullary and Pancreatic Cancer registry. RESULTS: In total 9887 patients are listed in the registry; 8207 of those have malignant periampullary cancer. Approximately one-third (3282 patients) have had resections performed, including benign/premalignant resections. 30-day and 90-day mortality after pancreatoduodenectomy is 1.5% and 3.5%, respectively. The overall 3-year survival for resected pancreatic ductal adenocarcinoma is 35%. Regional variations decreased over the studied period, but still exist. CONCLUSION: Results from the Swedish National Registry are satisfactory and comparable to international standards. Trends over time show increasing resection rates and some improved results. Better collaboration and openness within pancreatic surgeons is an important side effect.
Authors: Mikael Öman; Yvonne Wettergren; Elisabeth Odin; Sofia Westermark; Peter Naredi; Oskar Hemmingsson; Helena Taflin Journal: Cancer Chemother Pharmacol Date: 2021-06-16 Impact factor: 3.333
Authors: Emil Sahlström; Johan Nilsson; Bobby Tingstedt; Magnus Bergenfeldt; Roland Andersson; Bodil Andersson Journal: Scand J Surg Date: 2020-04-17 Impact factor: 2.360