Krishna Deepti Mogili1, Reka Karuppusami2, Sumi Thomas1, Achamma Chandy1, Mohan S Kamath3, Aleyamma Tk1. 1. Reproductive Medicine Unit, Christian Medical College Hospital, Vellore, India. 2. Department of Biostatistics, Christian Medical College Hospital, Vellore, India. 3. Reproductive Medicine Unit, Christian Medical College Hospital, Vellore, India. Electronic address: dockamz@gmail.com.
Abstract
OBJECTIVE: The main purpose of this study was to determine the prevalence of vitamin D deficiency in infertile women with polycystic ovarian syndrome (PCOS) and to explore the association of hypovitaminosis D with metabolic syndrome in women with PCOS. STUDY DESIGN: A prospective observational study was conducted in a tertiary care, infertility centre from March 2016 to March 2017. The primary outcome was estimation of the prevalence of vitamin D deficiency in infertile PCOS women. Secondary outcomes were to study the association of hypovitaminosis D with metabolic syndrome, obesity and hypercholesterolemia in PCOS patients. RESULTS: A total of 256 infertile women with PCOS were included in the study. Vitamin D deficiency was observed in 70.3% women, 20.3% were vitamin D insufficient and only 9.4% were vitamin D sufficient. Metabolic syndrome was seen in 80/256 (31.25%) women. There was no evidence of an association between hypovitaminosis D and metabolic syndrome, obesity or hyperlipidemia. There was a strong evidence of an association between waist circumference of >80 cm and vitamin D deficiency (p = 0.02). CONCLUSION: Vitamin D deficiency is highly prevalent in infertile PCOS women and there seems to be no association between hypovitaminosis D and the metabolic syndrome in the same population.
OBJECTIVE: The main purpose of this study was to determine the prevalence of vitamin Ddeficiency in infertilewomen with polycystic ovarian syndrome (PCOS) and to explore the association of hypovitaminosis D with metabolic syndrome in women with PCOS. STUDY DESIGN: A prospective observational study was conducted in a tertiary care, infertility centre from March 2016 to March 2017. The primary outcome was estimation of the prevalence of vitamin Ddeficiency in infertile PCOSwomen. Secondary outcomes were to study the association of hypovitaminosis D with metabolic syndrome, obesity and hypercholesterolemia in PCOSpatients. RESULTS: A total of 256 infertile women with PCOS were included in the study. Vitamin D deficiency was observed in 70.3% women, 20.3% were vitamin Dinsufficient and only 9.4% were vitamin D sufficient. Metabolic syndrome was seen in 80/256 (31.25%) women. There was no evidence of an association between hypovitaminosis D and metabolic syndrome, obesity or hyperlipidemia. There was a strong evidence of an association between waist circumference of >80 cm and vitamin D deficiency (p = 0.02). CONCLUSION:Vitamin D deficiency is highly prevalent in infertile PCOSwomen and there seems to be no association between hypovitaminosis D and the metabolic syndrome in the same population.
Authors: K Lajtai; R Tarszabó; B Bányai; B Péterffy; D Gerszi; É Ruisanchez; R E Sziva; Á Korsós-Novák; R Benkő; L Hadjadj; Z Benyó; E M Horváth; G Masszi; S Várbíró Journal: Oxid Med Cell Longev Date: 2021-03-18 Impact factor: 6.543
Authors: Mazin H Daghestani; Maha H Daghestani; Arjumand Warsy; Afaf El-Ansary; Mohammed A Omair; Maha A Omair; Lena M Hassen; Eman Mh Alhumaidhi; Bashaer Al Qahtani; Abdel Halim Harrath Journal: Front Endocrinol (Lausanne) Date: 2021-05-26 Impact factor: 5.555
Authors: Krisztina Lajtai; Csilla Terézia Nagy; Róbert Tarszabó; Rita Benkő; Leila Hadjadj; Réka Eszter Sziva; Dóra Gerszi; Bálint Bányai; Péter Ferdinandy; György László Nádasy; Zoltán Giricz; Eszter Mária Horváth; Szabolcs Várbíró Journal: Biomolecules Date: 2019-09-10