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Literature DB >> 3009536

Effect of using heat-inactivated serum with the Abbott human T-cell lymphotropic virus type III antibody test.

Abstract

The Abbott enzyme immunoassay (Abbott Laboratories, North Chicago, Ill.) for human T-cell lymphotropic virus type III (HTLV-III) antibody was evaluated to determine the effect of using heat-inactivated (56 degrees C for 30 min) serum as the sample. Each of 58 nonreactive serum samples gave a higher A492 value when tested after heat inactivation. Ten of the samples became reactive after heating. Heat-inactivated serum should not be used in the current Abbott HTLV-III antibody test, because this can cause false-positive results.

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Year: 1986 PMID： 3009536 PMCID： PMC268649 DOI： 10.1128/jcm.23.2.381-382.1986

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

8 in total

1. Risk of nosocomial infection with human T-cell lymphotropic virus III (HTLV-III).

Authors: M S Hirsch; G P Wormser; R T Schooley; D D Ho; D Felsenstein; C C Hopkins; C Joline; F Duncanson; M G Sarngadharan; C Saxinger
Journal: N Engl J Med Date: 1985-01-03 Impact factor: 91.245

2. AIDS--safety practices for clinical and research laboratories.

Authors: J V Federico; R R Gershon
Journal: Infect Control Date: 1984-04

3. Screening test for HTLV-III (AIDS agent) antibodies. Specificity, sensitivity, and applications.

Authors: S H Weiss; J J Goedert; M G Sarngadharan; A J Bodner; R C Gallo; W A Blattner
Journal: JAMA Date: 1985-01-11 Impact factor: 56.272

4. Frequent transmission of HTLV-III among spouses of patients with AIDS-related complex and AIDS.

Authors: R R Redfield; P D Markham; S Z Salahuddin; M G Sarngadharan; A J Bodner; T M Folks; W R Ballou; D C Wright; R C Gallo
Journal: JAMA Date: 1985-03-15 Impact factor: 56.272

5. Antibodies reactive with human T-lymphotropic retroviruses (HTLV-III) in the serum of patients with AIDS.

Authors: M G Sarngadharan; M Popovic; L Bruch; J Schüpbach; R C Gallo
Journal: Science Date: 1984-05-04 Impact factor: 47.728

6. Acquired immunodeficiency syndrome (AIDS) associated with transfusions.

Authors: J W Curran; D N Lawrence; H Jaffe; J E Kaplan; L D Zyla; M Chamberland; R Weinstein; K J Lui; L B Schonberger; T J Spira
Journal: N Engl J Med Date: 1984-01-12 Impact factor: 91.245

7. Thermal inactivation of the acquired immunodeficiency syndrome virus, human T lymphotropic virus-III/lymphadenopathy-associated virus, with special reference to antihemophilic factor.

Authors: J S McDougal; L S Martin; S P Cort; M Mozen; C M Heldebrant; B L Evatt
Journal: J Clin Invest Date: 1985-08 Impact factor: 14.808

8. The incidence rate of acquired immunodeficiency syndrome in selected populations.

Authors: A M Hardy; J R Allen; W M Morgan; J W Curran
Journal: JAMA Date: 1985-01-11 Impact factor: 56.272

8 in total

6 in total

Review 1. Frequency, causes, and new challenges of indeterminate results in Western blot confirmatory testing for antibodies to human immunodeficiency virus.

Authors: Ming Guan
Journal: Clin Vaccine Immunol Date: 2007-04-04

Effect of using heat-inactivated serum with the Abbott human T-cell lymphotropic virus type III antibody test.

1. Risk of nosocomial infection with human T-cell lymphotropic virus III (HTLV-III).

2. AIDS--safety practices for clinical and research laboratories.

3. Screening test for HTLV-III (AIDS agent) antibodies. Specificity, sensitivity, and applications.

4. Frequent transmission of HTLV-III among spouses of patients with AIDS-related complex and AIDS.

5. Antibodies reactive with human T-lymphotropic retroviruses (HTLV-III) in the serum of patients with AIDS.

6. Acquired immunodeficiency syndrome (AIDS) associated with transfusions.

7. Thermal inactivation of the acquired immunodeficiency syndrome virus, human T lymphotropic virus-III/lymphadenopathy-associated virus, with special reference to antihemophilic factor.

8. The incidence rate of acquired immunodeficiency syndrome in selected populations.

Review 1. Frequency, causes, and new challenges of indeterminate results in Western blot confirmatory testing for antibodies to human immunodeficiency virus.

2. False positive results with heated sera in Toxoplasma ELISA for IgG antibody.

Review 3. Laboratory tests for detection of human immunodeficiency virus type 1 infection.

4. Natural hidden autoantibodies to tissue transglutaminase cross-react with fibrinogen.

5. Inactivation of human immunodeficiency virus in serum specimens as a safety measure for diagnostic immunoassays.

6. Differential effects of serum heat treatment on chemotaxis and phagocytosis by human neutrophils.