Literature DB >> 30095227

Is pulse oximetry helpful for the early detection of critical congenital heart disease at high altitude?

Fabricio González-Andrade1, Daniel Echeverría1, Valeria López1, Michaela Arellano1.   

Abstract

OBJECTIVE: To assess the pulse oximetry as a method for screening critical congenital heart disease (CHD) in newborns. STUDY
DESIGN: This is an observational, transversal, descriptive simple study. The pre-ductal and postductal saturation were taken in term newborns that fulfilled the criteria of inclusion and exclusion in the Hospital Gineco-Obstetrico Isidro Ayora (HGOIA) in Quito. These measurements were performed between the 24 and 48 h after birth. Those newborns that saturated less than 90% on initial pulse oxìmetry underwent 3 successive measurements at 1-h intervals. Those who saturate less than 90% after 3 measurements or have a difference higher than 3% in preductal saturation and postductal saturation (positive screening) underwent transthoracic echocardiography evaluate for CHD.
RESULTS: Pulse oximetry from 963 newborns was evaluated. In Quito, at an altitude of 2820 meters above sea level (9252 feet), the mean preductal saturation was 92.76% (SD ± 3) and the postductal saturation, 93.76% (SD ± 4.7). Pulse oximetry in 53 patients (5.5%) was classified as a positive screening. No critical congenital heart diseases were found. Atrial septal defect (ASD) was the most common finding in a 46.94% (n = 23), followed by the association of patent ductus arteriosus (PDA) and ASD with a 12.24% (n = 6).
CONCLUSION: In this cohort of patients who underwent screening pulse oximetry, no critical congenital heart diseases (CHD) were observed. However, identifying those with oxygen saturation less than 90% after 3 successive measurements or a pre- and postductal oxygen difference of > 3% resulted in successful identification of ASD and PDA. It is necessary to implement new cutoff points in saturation values to identify critical cardiac anomalies in cities placed at a high altitude. The use of pulse oximetry should be recommended in all the newborns.
© 2018 Wiley Periodicals, Inc.

Entities:  

Keywords:  Ecuador; critical congenital heart disease; early detection; high altitude; newborns; pulse oximetry

Mesh:

Substances:

Year:  2018        PMID: 30095227     DOI: 10.1111/chd.12654

Source DB:  PubMed          Journal:  Congenit Heart Dis        ISSN: 1747-079X            Impact factor:   2.007


  2 in total

1.  Establishing the reference interval for pulse oxygen saturation in neonates at high altitudes: protocol for a multicentre, open, cross-sectional study.

Authors:  Bo Wang; Chongde Liu; Yanli Yao; Zhihui Lu; Rong Yu; Zhuoma CaiRen; Zhixiu Wang; Runwu Liu; Yazhen Wu; Zhangbin Yu
Journal:  BMJ Open       Date:  2022-04-22       Impact factor: 3.006

2.  Oxygen Saturation Behavior by Pulse Oximetry in Female Athletes: Breaking Myths.

Authors:  Pilar Martín-Escudero; Ana María Cabanas; Manuel Fuentes-Ferrer; Mercedes Galindo-Canales
Journal:  Biosensors (Basel)       Date:  2021-10-14
  2 in total

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