BACKGROUND: Poor sleep quality is common among patients with gastrointestinal (GI) disorders. However, few studies have assessed the presence of insomnia or reported circadian preferences and none have directly compared sleep between common GI conditions. AIMS: To compare clinical sleep characteristics in patients presenting to a tertiary care GI clinic for irritable bowel syndrome (IBS), functional dyspepsia (FD), inflammatory bowel disease (IBD), gastroesophageal reflux disease (GERD), and celiac disease (CD). METHODS: Validated sleep measures were administered to consecutive patients if they were diagnosed with IBS, IBD in clinical remission, CD, FD, or GERD. Healthy Controls (HCs) with no reported GI diagnoses or symptoms were also recruited. RESULTS: A total of 212 eligible respondents completed this survey, 161 GI clinic patients (IBS (n = 48), GERD (n = 29), IBD in clinical remission (n = 44), CD (n = 40)), and 41 HCs. Only, 10 respondents had a diagnosis of FD, and these were excluded. The IBS group had the highest frequency of poor sleep (72%) followed by CD (61%), GERD (60%), IBD (54%), and HC (39%). IBS patients also had the highest frequency of clinical insomnia (51%), followed by GERD (37%), CD (35%), IBD (27%), and HC (18%). 40% of IBS patients reported taking sleep medications at least once per week, compared to 32% of GERD, 23% IBD, 13% CD, and 15% HC. CONCLUSIONS: Patients presenting to a tertiary care GI clinic report poorer sleep than healthy controls. In general, patients with IBS report the highest rates of sleep difficulties compared to patients with other diagnoses.
BACKGROUND: Poor sleep quality is common among patients with gastrointestinal (GI) disorders. However, few studies have assessed the presence of insomnia or reported circadian preferences and none have directly compared sleep between common GI conditions. AIMS: To compare clinical sleep characteristics in patients presenting to a tertiary care GI clinic for irritable bowel syndrome (IBS), functional dyspepsia (FD), inflammatory bowel disease (IBD), gastroesophageal reflux disease (GERD), and celiac disease (CD). METHODS: Validated sleep measures were administered to consecutive patients if they were diagnosed with IBS, IBD in clinical remission, CD, FD, or GERD. Healthy Controls (HCs) with no reported GI diagnoses or symptoms were also recruited. RESULTS: A total of 212 eligible respondents completed this survey, 161 GI clinic patients (IBS (n = 48), GERD (n = 29), IBD in clinical remission (n = 44), CD (n = 40)), and 41 HCs. Only, 10 respondents had a diagnosis of FD, and these were excluded. The IBS group had the highest frequency of poor sleep (72%) followed by CD (61%), GERD (60%), IBD (54%), and HC (39%). IBSpatients also had the highest frequency of clinical insomnia (51%), followed by GERD (37%), CD (35%), IBD (27%), and HC (18%). 40% of IBSpatients reported taking sleep medications at least once per week, compared to 32% of GERD, 23% IBD, 13% CD, and 15% HC. CONCLUSIONS:Patients presenting to a tertiary care GI clinic report poorer sleep than healthy controls. In general, patients with IBS report the highest rates of sleep difficulties compared to patients with other diagnoses.
Authors: Andreas Hinz; Heide Glaesmer; Elmar Brähler; Markus Löffler; Christoph Engel; Cornelia Enzenbach; Ulrich Hegerl; Christian Sander Journal: Sleep Med Date: 2016-05-04 Impact factor: 3.492
Authors: A Patel; S Hasak; B Cassell; M A Ciorba; E E Vivio; M Kumar; C Prakash Gyawali; G S Sayuk Journal: Aliment Pharmacol Ther Date: 2016-05-30 Impact factor: 8.171
Authors: Diana Taibi Buchanan; Kevin Cain; Margaret Heitkemper; Robert Burr; Michael V Vitiello; Jasmine Zia; Monica Jarrett Journal: J Clin Sleep Med Date: 2014-09-15 Impact factor: 4.062
Authors: F Zingone; M Siniscalchi; P Capone; R Tortora; P Andreozzi; E Capone; C Ciacci Journal: Aliment Pharmacol Ther Date: 2010-08-16 Impact factor: 8.171
Authors: Ran Yan; Mandy Murphy; Angela Genoni; Evania Marlow; Ian C Dunican; Johnny Lo; Lesley Andrew; Amanda Devine; Claus T Christophersen Journal: BMJ Open Gastroenterol Date: 2020-08
Authors: Jessica K Salwen-Deremer; Michael T Smith; Hannah G Haskell; Colleen Schreyer; Corey A Siegel Journal: Dig Dis Sci Date: 2021-07-30 Impact factor: 3.487