| Literature DB >> 30094532 |
Chirag Bavishi1, Dhaval Kolte1, Paul C Gordon1, J Dawn Abbott2.
Abstract
Severe aortic stenosis (AS) and heart failure (HF) represent an important and high-risk group of patients who are often referred for transcatheter aortic valve replacement (TAVR) due to high risk for surgical intervention. Thus far, randomized controlled trials have shown comparable outcomes between TAVR and surgical aortic valve replacement in patients with severe AS and heart failure with reduced ejection fraction. In the current review, we will discuss (1) the pathophysiology of HF in patients with severe AS, (2) role of imaging modalities in management, (3) role of biomarkers of HF on prognosis, (4) impact of other valvular heart diseases, (5) evidence from the contemporary trials on the role of TAVR in patients with severe AS and HF, and (6) future directions and research.Entities:
Keywords: Aortic stenosis; Heart failure; Valvular heart disease
Mesh:
Year: 2018 PMID: 30094532 DOI: 10.1007/s10741-018-9726-8
Source DB: PubMed Journal: Heart Fail Rev ISSN: 1382-4147 Impact factor: 4.214