John D Serfas1, Priyesh A Patel1, Richard A Krasuski2. 1. Duke University Medical Center, Durham, NC, USA. 2. Duke University Medical Center, Durham, NC, USA. richard.krasuski@duke.edu.
Abstract
PURPOSE OF REVIEW: To assess current management strategies for advanced heart failure in adults with congenital heart disease, including heart transplantation and mechanical circulatory support. RECENT FINDINGS: Current data demonstrate that adults with CHD generally experience higher short-term mortality after heart transplantation and MCS implantation, but enjoy superior long-term survival. Such patients are nonetheless less likely to receive a transplant than non-ACHD peers due to a variety of factors, including lack of applicability of current listing criteria to HF in ACHD. MCS is underutilized in ACHD, but provides similar quality of life benefits for ACHD and non-ACHD patients alike. Heart failure in ACHD is complex and difficult to treat, and both heart transplantation and mechanical circulatory support are often challenging to implement in this patient population. However, long-term results are encouraging, and existing data supports increasing use of MCS and transplant earlier in their disease course. Multidisciplinary care is critical to success in these complex patients.
PURPOSE OF REVIEW: To assess current management strategies for advanced heart failure in adults with congenital heart disease, including heart transplantation and mechanical circulatory support. RECENT FINDINGS: Current data demonstrate that adults with CHD generally experience higher short-term mortality after heart transplantation and MCS implantation, but enjoy superior long-term survival. Such patients are nonetheless less likely to receive a transplant than non-ACHD peers due to a variety of factors, including lack of applicability of current listing criteria to HF in ACHD. MCS is underutilized in ACHD, but provides similar quality of life benefits for ACHD and non-ACHD patients alike. Heart failure in ACHD is complex and difficult to treat, and both heart transplantation and mechanical circulatory support are often challenging to implement in this patient population. However, long-term results are encouraging, and existing data supports increasing use of MCS and transplant earlier in their disease course. Multidisciplinary care is critical to success in these complex patients.
Authors: H J Reich; M Awad; A Ruzza; M A De Robertis; D Ramzy; N Nissen; S Colquhoun; F Esmailian; A Trento; J Kobashigawa; L S Czer Journal: Transplant Proc Date: 2015-11 Impact factor: 1.066
Authors: Keith D Aaronson; Mark S Slaughter; Leslie W Miller; Edwin C McGee; William G Cotts; Michael A Acker; Mariell L Jessup; Igor D Gregoric; Pranav Loyalka; O H Frazier; Valluvan Jeevanandam; Allen S Anderson; Robert L Kormos; Jeffrey J Teuteberg; Wayne C Levy; David C Naftel; Richard M Bittman; Francis D Pagani; David R Hathaway; Steven W Boyce Journal: Circulation Date: 2012-05-22 Impact factor: 29.690
Authors: D Bernstein; D Naftel; C Chin; L J Addonizio; P Gamberg; E D Blume; D Hsu; C E Canter; J K Kirklin; W R Morrow Journal: Circulation Date: 2006-07-17 Impact factor: 29.690
Authors: Leslie W Miller; Francis D Pagani; Stuart D Russell; Ranjit John; Andrew J Boyle; Keith D Aaronson; John V Conte; Yoshifumi Naka; Donna Mancini; Reynolds M Delgado; Thomas E MacGillivray; David J Farrar; O H Frazier Journal: N Engl J Med Date: 2007-08-30 Impact factor: 91.245
Authors: Jacqueline M Lamour; Kirk R Kanter; David C Naftel; Maryanne R Chrisant; William R Morrow; Barry S Clemson; James K Kirklin Journal: J Am Coll Cardiol Date: 2009-07-07 Impact factor: 24.094
Authors: Jill M Gelow; Howard K Song; Joseph B Weiss; James O Mudd; Craig S Broberg Journal: J Heart Lung Transplant Date: 2013-08-06 Impact factor: 10.247
Authors: Alexander C Egbe; Heidi M Connolly; William R Miranda; Naser M Ammash; Donald J Hagler; Gruschen R Veldtman; Barry A Borlaug Journal: Circ Heart Fail Date: 2017-12 Impact factor: 8.790
Authors: Bryan G Maxwell; Jim K Wong; Ahmad Y Sheikh; Peter H U Lee; Robert L Lobato Journal: Eur J Cardiothorac Surg Date: 2013-10-17 Impact factor: 4.191
Authors: Joshua Saef; Robert Montgomery; Ari Cedars; Wai H Wilson Tang; Joseph W Rossano; Katsuhide Maeda; Yuli Y Kim; Sumeet S Vaikunth Journal: J Clin Med Date: 2022-06-03 Impact factor: 4.964