Literature DB >> 3009226

Solid-phase peptide synthesis of human(Nle-27)-oxyntomodulin. Preliminary evaluation of its biological activities.

M P Audousset-Puech, M Dufour, A Kervran, C Jarrousse, B Castro, D Bataille, J Martinez.   

Abstract

Oxyntomodulin is a peptide isolated from porcine intestine which consists of the whole glucagon sequence extended at its C-terminal part by a basic octapeptide. The analogue (Nle-27)-oxyntomodulin of the human sequence has been synthesized by solid-phase peptide synthesis, purified by HPLC and identified. Its biological activities are the same as those of the natural hormone.

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Year:  1986        PMID: 3009226     DOI: 10.1016/0014-5793(86)80535-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  2 in total

1.  Oxyntomodulin reduces hydromineral transport through rat small intestine.

Authors:  F Beauclair; B Eto; D Pansu; G Rodier; T Mochizuki; J Martinez; D Bataille; C Jarrousse
Journal:  Dig Dis Sci       Date:  1998-08       Impact factor: 3.199

2.  N-acetyl oxyntomodulin30-37: pharmacokinetics and activity on gastric acid secretion.

Authors:  C Carles-Bonnet; C Jarrousse; H Niel; J Martinez; M Rolland; D Bataille
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1992-01       Impact factor: 3.000

  2 in total

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