Literature DB >> 30092208

Small RNAs, but Sizable Itch: TRPA1 Activation by an Extracellular MicroRNA.

Tayler D Sheahan1, Junichi Hachisuka1, Sarah E Ross2.   

Abstract

Chronic itch is a major symptom of cutaneous T cell lymphoma (CTCL). In this issue of Neuron, Han and colleagues (2018) provide evidence that one of the itch mediators in CTCL is an extracellular miRNA that directly activates TRPA1 on sensory neurons.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID： 30092208     DOI： 10.1016/j.neuron.2018.07.040

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  3 in total

1.  Transient receptor potential ankyrin1 channel is endogenously expressed in T cells and is involved in immune functions.

Authors:  Subhransu Sekhar Sahoo; Rakesh Kumar Majhi; Ankit Tiwari; Tusar Acharya; P Sanjai Kumar; Somdatta Saha; Abhishek Kumar; Chandan Goswami; Subhasis Chattopadhyay
Journal:  Biosci Rep       Date:  2019-09-20       Impact factor: 3.840

Review 2.  TRP Channels as Drug Targets to Relieve Itch.

Authors:  Zili Xie; Hongzhen Hu
Journal:  Pharmaceuticals (Basel)       Date:  2018-10-06

3.  Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch.

Authors:  Santosh K Mishra; Joshua J Wheeler; Saumitra Pitake; Huiping Ding; Changyu Jiang; Tomoki Fukuyama; Judy S Paps; Patrick Ralph; Jacob Coyne; Michelle Parkington; Jennifer DeBrecht; Lauren C Ehrhardt-Humbert; Glenn P Cruse; Wolfgang Bäumer; Ru-Rong Ji; Mei-Chuan Ko; Thierry Olivry
Journal:  Cell Rep       Date:  2020-04-07       Impact factor: 9.995
  3 in total

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