Literature DB >> 3009042

Cross-linking between histones and DNA following treatment with a series of dimethane sulphonate esters.

J A Hartley, B W Fox.   

Abstract

The cross-linking of the nucleohistone to the associated DNA by a series of methanesulphonates of the busulphan series (CH3SO2O(CH2)nOSO2CH3) from n = 4-9 has been studied by gel electrophoresis, by the use of 35S labelling and by pyrenemaleimide competition. It has been shown that all the dimethanesulphonates react with the Cys 114 of histone H3, and that octamethylene dimethanesulphonate (n = 8) cross-links histone H3 with DNA via the sulphydryl group, as well as forming H3-H3 dimers.

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Year:  1986        PMID： 3009042     DOI： 10.1007/bf00299867

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN： 0344-5704            Impact factor:   3.333


  31 in total

1.  The mode of action of alkylating agents. II. Studies of the metabolism of myleran. The reaction of myleran with some naturally occurring thiols in vitro.

Authors:  J J ROBERTS; G P WARWICK
Journal:  Biochem Pharmacol       Date:  1961-06       Impact factor: 5.858

2.  Myleran in chronic myeloid leukaemia; results of treatment.

Authors:  D A GALTON
Journal:  Lancet       Date:  1953-01-31       Impact factor: 79.321

3.  The effects of nonane on malignant disease.

Authors:  E MILLER
Journal:  Cancer Chemother Rep       Date:  1961-10

Review 4.  Antispermatogenic agents.

Authors:  H Jackson
Journal:  Br Med Bull       Date:  1970-01       Impact factor: 4.291

5.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

6.  Ultraviolet light induced preferential cross-linking of histone H3 to deoxyribonucleic acid in chromatin and nuclei of chicken erythrocytes.

Authors:  T M Cao; M T Sung
Journal:  Biochemistry       Date:  1982-07-06       Impact factor: 3.162

7.  The interaction of platinum complexes with nucleosomes investigated with fluorescent probes.

Authors:  L M Thompson; M Arquilla; H Simpkins
Journal:  Biochim Biophys Acta       Date:  1982-08-30

8.  Chemical cross-linking of H1 histone to the nucleosomal histones.

Authors:  D Ring; R D Cole
Journal:  J Biol Chem       Date:  1979-11-25       Impact factor: 5.157

9.  DNA-DNA interstrand crosslinking by dimethyanesulphonic acid esters. Correlation with cytotoxicity and antitumour activity in the Yoshida lymphosarcoma model and relationship to chain length.

Authors:  P Bedford; B W Fox
Journal:  Biochem Pharmacol       Date:  1983-08-01       Impact factor: 5.858

10.  A simple and rapid method for the isolation of enzymatically active HeLa cell nuclei.

Authors:  D M Berkowitz; T Kakefuda; M Sporn
Journal:  J Cell Biol       Date:  1969-09       Impact factor: 10.539
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  3 in total

Review 1.  Clarifying busulfan metabolism and drug interactions to support new therapeutic drug monitoring strategies: a comprehensive review.

Authors:  Alan L Myers; Jitesh D Kawedia; Richard E Champlin; Mark A Kramer; Yago Nieto; Romi Ghose; Borje S Andersson
Journal:  Expert Opin Drug Metab Toxicol       Date:  2017-08-17       Impact factor: 4.481

2.  Relationships between ablation of distinct haematopoietic cell subsets and the development of donor bone marrow engraftment following recipient pretreatment with different alkylating drugs.

Authors:  J D Down; A Boudewijn; J H Dillingh; B W Fox; R E Ploemacher
Journal:  Br J Cancer       Date:  1994-10       Impact factor: 7.640

3.  Protective effect of curcumin on busulfan-induced renal toxicity in male rats.

Authors:  Mohammad-Amin Abdollahifar; Vahid Ebrahimi; Abbas Aliaghaei; Amir Raoofi; Amirreza Khosravi; Amirhosein Hasani; Ali Mehdizadeh; Mohammad Asadi
Journal:  Ren Fail       Date:  2020-11       Impact factor: 2.606
  3 in total

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